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A new generation of ferrociphenols leads to a...
Journal article

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

Abstract

Organometallic compounds bearing the redox motif [ferrocenyl-ene-phenol] have very promising antiproliferative properties which have been further improved by incorporating pertinent substituents able to engender new mechanisms. Here we show that novel ferrociphenols bearing a hydroxypropyl chain exhibit strong antiproliferative effects, in most cases much better than those of cisplatin, tamoxifen, or of previously described ferrociphenols …

Authors

Wang Y; Dansette PM; Pigeon P; Top S; McGlinchey MJ; Mansuy D; Jaouen G

Journal

Chemical Science, Vol. 9, No. 1, pp. 70–78

Publisher

Royal Society of Chemistry (RSC)

Publication Date

2018

DOI

10.1039/c7sc04213b

ISSN

2041-6520

Labels

Fields of Research (FoR)