Journal article
Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
Abstract
BACKGROUND: The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear.
METHODS: In this multicenter, open-label, noninferiority trial, we randomly assigned 5243 adults undergoing cardiac surgery who had a European System for Cardiac Operative Risk Evaluation (EuroSCORE) I of 6 or more (on a scale from 0 to 47, with higher scores indicating a higher risk …
Authors
Mazer CD; Whitlock RP; Fergusson DA; Hall J; Belley-Cote E; Connolly K; Khanykin B; Gregory AJ; de Médicis É; McGuinness S
Journal
The New England Journal of Medicine, Vol. 377, No. 22, pp. 2133–2144
Publisher
Massachusetts Medical Society
Publication Date
November 30, 2017
DOI
10.1056/nejmoa1711818
ISSN
0028-4793