A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study Academic Article uri icon

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abstract

  • INTRODUCTION: Hearing loss (HL) is prevalent and independently related to cognitive decline and dementia. There has never been a randomized trial to test if HL treatment could reduce cognitive decline in older adults. METHODS: A 40-person (aged 70-84 years) pilot study in Washington County, MD, was conducted. Participants were randomized 1:1 to a best practices hearing or successful aging intervention and followed for 6 months. clinicaltrials.gov Identifier: NCT02412254. RESULTS: The Aging and Cognitive Health Evaluation in Elders Pilot (ACHIEVE-P) Study demonstrated feasibility in recruitment, retention, and implementation of interventions with no treatment-related adverse events. A clear efficacy signal of the hearing intervention was observed in perceived hearing handicap (mean of 0.11 to -1.29 standard deviation [SD] units; lower scores better) and memory (mean of -0.10 SD to 0.38 SD). DISCUSSION: ACHIEVE-P sets the stage for the full-scale ACHIEVE trial (N = 850, recruitment beginning November 2017), the first randomized trial to determine efficacy of a best practices hearing (vs. successful aging) intervention on reducing cognitive decline in older adults with HL.

authors

  • Deal, Jennifer A
  • Albert, Marilyn S
  • Arnold, Michelle
  • Bangdiwala, Shrikant
  • Chisolm, Theresa
  • Davis, Sonia
  • Eddins, Ann
  • Glynn, Nancy W
  • Goman, Adele M
  • Minotti, Melissa
  • Mosley, Thomas
  • Rebok, George W
  • Reed, Nicholas
  • Rodgers, Elizabeth
  • Sanchez, Victoria
  • Sharrett, A Richey
  • Coresh, Josef
  • Lin, Frank R

publication date

  • September 2017