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Fondaparinux for the Treatment of Superficial-Vein...
Journal article

Fondaparinux for the Treatment of Superficial-Vein Thrombosis in the Legs

Abstract

BACKGROUND: The efficacy and safety of anticoagulant treatment for patients with acute, symptomatic superficial-vein thrombosis in the legs, but without concomitant deep-vein thrombosis or symptomatic pulmonary embolism at presentation, have not been established. METHODS: In a randomized, double-blind trial, we assigned 3002 patients to receive either fondaparinux, administered subcutaneously at a dose of 2.5 mg once daily, or placebo for 45 …

Authors

Decousus H; Prandoni P; Mismetti P; Bauersachs RM; Boda Z; Brenner B; Laporte S; Matyas L; Middeldorp S; Sokurenko G

Journal

The New England Journal of Medicine, Vol. 363, No. 13, pp. 1222–1232

Publisher

Massachusetts Medical Society

Publication Date

September 23, 2010

DOI

10.1056/nejmoa0912072

ISSN

0028-4793