P114 Repeat mismatch in renal transplantation: Is the original source of repeat mismatch more predictive than cPRA for antibody response post transplant?

The calculated panel reactive antibody (cPRA) value has been regarded as a predictor of rejection and allograft loss. Broad sensitization against HLA antigens characterized by a high cPRA value often results in intensification of induction and maintenance immunosuppression. Similarly, repeat mismatch HLA proteins between first transplants or pregnancy exposure and second transplants are thought to be potential stimuli for immune memory …