Journal article
Radiation fractionation: the search for isoeffect relationships and mechanisms
Abstract
PURPOSE: Review the historical basis for the use of fractionated radiation in radiation oncology.
CONCLUSION: The history of dose fractionation in radiation oncology is long and tortuous, and the radiobiologist's understanding of why fractionation worked came decades after radiation oncologists had adopted multi-week daily-dose fractionation as 'standard'. Central to the history is the search for 'isoeffective' formulas that would allow …
Authors
Moulder JE; Seymour C
Journal
International Journal of Radiation Biology, Vol. 94, No. 8, pp. 743–751
Publisher
Taylor & Francis
Publication Date
July 28, 2018
DOI
10.1080/09553002.2017.1376764
ISSN
0955-3002