Characterizing Protein Arginine Methyltransferase Expression, Localization, and Function During Myogenesis

Protein arginine methyltransferases (PRMTs) play a critical role in the development of skeletal muscle. Despite the importance of PRMTs, the expression, localization, and function of these enzymes, specifically PRMT1, PRMT4, and PRMT5, during muscle development remains poorly understood. Therefore, the purpose of our study was to investigate quantitative, temporal, spatial, and functional metrics of PRMT biology in skeletal muscle cells during …