Journal article
Chronic Kidney Disease, Basal Insulin Glargine, and Health Outcomes in People with Dysglycemia: The ORIGIN Study
Abstract
BACKGROUND: Early stages of chronic kidney disease are associated with an increased cardiovascular risk in patients with established type 2 diabetes and macrovascular disease. The role of early stages of chronic kidney disease on macrovascular outcomes in prediabetes and early type 2 diabetes mellitus is not known. In the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, the introduction of insulin had no effect on …
Authors
Papademetriou V; Nylen ES; Doumas M; Probstfield J; Mann JFE; Gilbert RE; Gerstein HC
Journal
The American Journal of Medicine, Vol. 130, No. 12, pp. 1465.e27–1465.e39
Publisher
Elsevier
Publication Date
December 2017
DOI
10.1016/j.amjmed.2017.05.047
ISSN
0002-9343