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De novo mutations in the actin genes ACTB and...
Journal article

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome

Abstract

William Dobyns, Daniela Pilz and colleagues show that de novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome, a developmental disorder characterized by distinct craniofacial features, ocular colobomata and defects in neuronal migration.

Authors

Rivière J-B; van Bon BWM; Hoischen A; Kholmanskikh SS; O'Roak BJ; Gilissen C; Gijsen S; Sullivan CT; Christian SL; Abdul-Rahman OA

Journal

Nature Genetics, Vol. 44, No. 4, pp. 440–444

Publisher

Springer Nature

Publication Date

4 2012

DOI

10.1038/ng.1091

ISSN

1061-4036