Journal article
Effects of Metoprolol CR in Patients With Ischemic and Dilated Cardiomyopathy
Abstract
BACKGROUND: Metoprolol provides clinical benefits in patients with congestive heart failure (CHF). In this study, we investigated the effects of controlled-release metoprolol (metoprolol CR) on clinical status, on left ventricular (LV) volumes and function, and on neurohumoral activation in a large number of patients with CHF of mixed causes.
METHODS AND RESULTS: Four hundred twenty-six patients with symptomatic CHF were randomized to receive …
Journal
Circulation, Vol. 101, No. 4, pp. 378–384
Publisher
Wolters Kluwer
Publication Date
2 2000
DOI
10.1161/01.cir.101.4.378
ISSN
0009-7322