Journal article
Purification of transgenic tobacco-derived recombinant human monoclonal antibody
Abstract
Purification of recombinant monoclonal antibody from transgenic plant extract is technically challenging as it involves the processing of large volume of material, containing low titre of antibody, present along with large quantities of native proteins and other impurities. The conventional approach of capturing antibody from a clarified extract using packed-bed chromatography is therefore not particularly suitable. This study evaluates the …
Authors
Mayani M; Filipe CDM; McLean MD; Hall JC; Ghosh R
Journal
Biochemical Engineering Journal, Vol. 72, , pp. 33–41
Publisher
Elsevier
Publication Date
March 2013
DOI
10.1016/j.bej.2012.12.007
ISSN
1369-703X