Three decades of in vivo x‐ray fluorescence of lead in bone Conferences

abstract

• AbstractIn vivo measurements of lead in bone were first made in the early 1970s. Of the three systems that have been used (57Co excited K, 125I or polarized excited L, 109Cd excited K), 109Cd excited K x‐ray fluorescence has been most widely adopted. Bone lead measured in vivo has been shown to reflect cumulative exposure, but the rate of input to bone varies with level of exposure. Chelated lead does not relate directly to bone lead. Endogenous exposure has been highlighted by bone lead measurements and this release of lead from bone and hence the half‐life of lead in bone have been shown to depend on age and on intensity of lead exposure. Thus x‐ray spectrometry has made a significant contribution to the understanding of long‐term human lead metabolism. Copyright © 2005 John Wiley & Sons, Ltd.

authors

• Chettle, David

status

• published 

publication date

• September 2005

has subject area

• 01 Mathematical Sciences (FoR)
• 02 Physical Sciences (FoR)
• 03 Chemical Sciences (FoR)
• Analytical Chemistry (Science Metrix)

published in

• X-Ray Spectrometry  Journal

presented at event

• European Conference on X-Ray Spectrometry (EXRS 2004)  Conference

keywords

• BLOOD
• EXPOSURE
• INDEX
• INVIVO MEASUREMENT
• Science & Technology
• Spectroscopy
• TIBIA
• Technology

Digital Object Identifier (DOI)

• 10.1002/xrs.860

start page

• 446

end page

• 450

volume

• 34

issue

• 5