Simulation study of the fractionation of proteins using ultrafiltration

The effects of module hydrodynamics (cross-flow velocity) and permeate flux (pore velocity) on the selectivity of binary protein fractionation in tangential flow ultrafiltration are examined from a theoretical point of view in this paper. Simulation studies show that, for a given cross-flow velocity, the selectivity depends on the permeate flux, increasing with increase in permeate flux from a value of 1 to a maximum value (at a permeate flux …