Journal article
Time Course and Pattern of Blood Loss With Ibuprofen Treatment in Healthy Subjects
Abstract
BACKGROUND & AIMS: Nonselective nonsteroidal anti-inflammatory drug (NSAID) users are at increased risk of gastrointestinal bleeding. We aimed to assess the pattern and extent of fecal blood loss (FBL) with ibuprofen, which is considered to have a favorable gastrointestinal safety profile.
METHODS: We conducted a post hoc analysis of 2 separate randomized, parallel-group, double-blind studies, in which ibuprofen was used as a positive control. …
Authors
Bowen B; Yuan Y; James C; Rashid F; Hunt RH
Journal
Clinical Gastroenterology and Hepatology, Vol. 3, No. 11, pp. 1075–1082
Publisher
Elsevier
Publication Date
November 2005
DOI
10.1016/s1542-3565(05)00605-1
ISSN
1542-3565