An improved synthesis of m-diazirinophenol Journal Articles

abstract

• The published synthesis of phenolic diazirine was shown to result in products which were chlorinated during the hypochlorite oxidation while the desired unchlorinated product was lost during the usual work-up. A superior synthesis is described: inclusion of pyridine during the oxidation step prevents the chlorination; the desired volatile diazirine was isolated in good yield using silica gel and reverse phase high pressure liquid chromatography.

authors

• Leblanc, Pierre
• Gerber, Gerhard Ernst

status

• published 

publication date

• September 1, 1984

has subject area

• 03 Chemical Sciences (FoR)
• General Chemistry (Science Metrix)

published in

• Canadian Journal of Chemistry  Journal

keywords

• Chemistry
• Chemistry, Multidisciplinary
• Physical Sciences
• Science & Technology

Digital Object Identifier (DOI)

• 10.1139/v84-302

start page

• 1767

end page

• 1771

volume

• 62

issue

• 9