Journal article
Effects of a model androgen (methyl testosterone) and a model anti-androgen (cyproterone acetate) on reproductive endocrine endpoints in a short-term adult mummichog (Fundulus heteroclitus) bioassay
Abstract
A short-term gonadal recrudescence bioassay using the mummichog (Fundulus heteroclitus) was employed to examine the consequences of environmentally relevant and pharmacological exposures (1-1000 ng/l) of the androgen, 17alpha-methyl testosterone (MT), and the anti-androgen, cyproterone acetate (CA), on reproductive endocrine endpoints. Recrudescing male (GSI = approx. 2%) and female (GSI = approx. 10%) fish were exposed to graded concentrations …
Authors
Sharpe RL; MacLatchy DL; Courtenay SC; Van Der Kraak GJ
Journal
Aquatic Toxicology, Vol. 67, No. 3, pp. 203–215
Publisher
Elsevier
Publication Date
April 28, 2004
DOI
10.1016/j.aquatox.2004.01.009
ISSN
0166-445X