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Evolution of the RpoS Regulon: Origin of RpoS and...
Journal article

Evolution of the RpoS Regulon: Origin of RpoS and the Conservation of RpoS-Dependent Regulation in Bacteria

Abstract

The RpoS sigma factor in proteobacteria regulates genes in stationary phase and in response to stress. Although of conserved function, the RpoS regulon may have different gene composition across species due to high genomic diversity and to known environmental conditions that select for RpoS mutants. In this study, the distribution of RpoS homologs in prokaryotes and the differential dependence of regulon members on RpoS for expression in two …

Authors

Chiang SM; Schellhorn HE

Journal

Journal of Molecular Evolution, Vol. 70, No. 6, pp. 557–571

Publisher

Springer Nature

Publication Date

June 2010

DOI

10.1007/s00239-010-9352-0

ISSN

0022-2844