Plasminogen Adsorption to Sulfonated and Lysine Derivatized Model Silica Glass Materials

Silica glass and silylated silica glass have been used extensively as model surfaces for studying the interactions of biological systems with specific chemical functions. In this work, the adsorption of plasminogen to silylated silica glass materials has been investigated with the objective of providing data for the development of a profibrinolytic or clot lysing surface for blood-contacting applications. The adsorption of plasminogen from Tris …