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Effect of sulfonation of segmented polyurethanes...
Journal article

Effect of sulfonation of segmented polyurethanes on the transient adsorption of fibrinogen from plasma: Possible correlation with anticoagulant behavior

Abstract

The influence of polyurethane sulfonation on fibrinogen adsorption from plasma and on plasma coagulation has been investigated. Sulfonated polyurethanes were synthesized using a two-step solution polymerization in which a diamino disulfonic acid was used as chain extender, thus incorporating sulfonate groups into the hard segments. Polymer molecular weights were determined by size exclusion chromatography and weight average values were in the …

Authors

Santerre JP; Hove PT; VanderKamp NH; Brash JL

Journal

Journal of Biomedical Materials Research, Vol. 26, No. 1, pp. 39–57

Publisher

Wiley

Publication Date

January 1992

DOI

10.1002/jbm.820260105

ISSN

0021-9304