Journal article
Inhibitory effect of silicon nanowires on the polymerase chain reaction
Abstract
The effect of nanomaterials on biological reactions has received much attention. We report herein that silicon nanowires (SiNWs) inhibit the polymerase chain reaction (PCR). The inhibitory effect was found to be concentration-dependent, with a minimum inhibitory concentration of about 0.4 mg ml(-1). DNA polymerase, restriction endonucleases, lysozyme and horseradish peroxidase maintained their bioactivities after exposure to SiNWs. Also the …
Authors
Wang H; Wang L; Yuan L; Yang W; Brash JL; Chen H
Journal
Nanotechnology, Vol. 23, No. 36,
Publisher
IOP Publishing
Publication Date
September 14, 2012
DOI
10.1088/0957-4484/23/36/365101
ISSN
0957-4484