Journal article
Glutathione Peroxidase 1 Activity and Cardiovascular Events in Patients with Coronary Artery Disease
Abstract
BACKGROUND: Cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the control of reactive oxygen species. In vitro data and studies in animal models suggest that these enzymes may protect against atherosclerosis, but little is known about their relevance to human disease.
METHODS: We conducted a prospective study among 636 patients with suspected coronary artery disease, with a median …
Authors
Blankenberg S; Rupprecht HJ; Bickel C; Torzewski M; Hafner G; Tiret L; Smieja M; Cambien F; Meyer J; Lackner KJ
Journal
The New England Journal of Medicine, Vol. 349, No. 17, pp. 1605–1613
Publisher
Massachusetts Medical Society
Publication Date
October 23, 2003
DOI
10.1056/nejmoa030535
ISSN
0028-4793