Comparison of dacron and nylon-flocked self-collected vaginal swabs and urine for the detection of<i>Trichomonas vaginalis</i>using analyte-specific reagents in a transcription-mediated amplification assay: Table 1

ObjectivesTo compare self-collected vaginal swab (SCVS) types and first-catch urine (FCU) to diagnoseTrichomonas vaginalisusing analyte-specific reagents designed to be used in a transcription-mediated amplification assay.MethodsA total of 241 women (group A) collected a FCU and a SCVS using a dacron swab (APTIMA collection kit). A second group of 289 women (group B) collected two SCVS using one dacron swab and one nylon-flocked swab.ResultsOf 75 young women (street youth) determined to be infected withT vaginalisonly seven reported symptoms of vaginal discharge or irritation. Using a cutoff of 50 000 relative light units, the sensitivity and specificity was 97.2% and 97.6%, respectively for dacron SCVS compared with 41.7% and 100% for FCU in group A; 92.3% and 98.8% for dacron SCVS and 92.3% and 99.2% for flocked-nylon SCVS in group B. The assay tested 96 samples in 6 h.ConclusionsDacron and nylon-flocked SCVS performed equally well and significantly better than FCU using analyte-specific reagents in the APTIMA transcription-mediated amplification assay. Either swab type could be used for self-collection.

Comparison of dacron and nylon-flocked self-collected vaginal swabs and urine for the detection ofTrichomonas vaginalisusing analyte-specific reagents in a transcription-mediated amplification assay: Table 1 Journal Articles