Hospital-Based Surveillance for Rotavirus Gastroenteritis using Molecular Testing and Immunoassay During the 2011 Season in Botswana Journal Articles uri icon

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abstract

  • We describe rotavirus testing and clinical characteristics for children admitted with acute gastroenteritis during Botswana's 2011 rotavirus season. The rotavirus season extended from June to October with rotavirus-specific case fatality being 2.8%. Using molecular testing as reference, the immunochromatographic test had a sensitivity of 76.5% and specificity of 68.0%. Rotavirus vaccine may significantly reduce childhood morbidity and mortality in Botswana.

authors

  • Welch, Henry
  • Steenhoff, Andrew P
  • Chakalisa, Unoda
  • Arscott-Mills, Tonya
  • Mazhani, Loeto
  • Mokomane, Margaret
  • Foster-Fabiano, Sara
  • Wirth, Kathleen E
  • Skinn, Andrew
  • Pernica, Jeffrey
  • Smieja, Marek
  • Goldfarb, David M

publication date

  • May 2013