Conjugated linoleic acid reduces body fat and prevents seasonal weight gain among overweight adults

Conjugated linoleic acid (CLA) supplementation has been shown to reduce fat mass in animals, but results in humans have been inconsistent. To further test the effect of CLA on body composition, we conducted a randomized, double‐blind study in 40 overweight adults. For six months including the holiday season, 22 subjects took 3.2 g/d of a 50:50 mixture of cis‐9, trans‐11 and trans‐10, cis‐12 isomers of CLA and 18 subjects took a safflower oil …