Journal article
An efficient strategy for gene mapping using multipoint linkage analysis: exclusion of the multiple endocrine neoplasia 2A (MEN2A) locus from chromosome 13.
Abstract
Members of four families in which multiple endocrine neoplasia type 2A (MEN-2A) is segregating were typed for seven DNA markers and one red cell enzyme marker on chromosome 13. Close linkage was excluded between the MEN2A locus and each marker locus tested. By means of multipoint analysis and the genetic map of chromosome 13 developed by Leppert et al., MEN2A was excluded from any position between the most proximal marker locus (D13S6) and the …
Authors
Farrer LA; Goodfellow PJ; Lamarche CM; Franjkovic I; Myers S; White BN; Holden JJ; Kidd JR; Simpson NE; Kidd KK
Journal
American Journal of Human Genetics, Vol. 40, No. 4, pp. 329–337
Publication Date
April 1987
ISSN
0002-9297