Journal article
Intravenous Cyclophosphamide and Plasmapheresis in Dialysis-Dependent ANCA-Associated Vasculitis
Abstract
BACKGROUND AND OBJECTIVES: Induction therapy with oral cyclophosphamide (CYP) has been a mainstay of treatment in patients with severe renal failure secondary to ANCA-associated vasculitis (AAV). Recent evidence proposes using pulsed intravenous CYP in less severe disease to minimize adverse events. It is unclear if this can be translated to those with dialysis-dependent renal insufficiency.
DESIGN, SETTING, PARTICIPANTS, & METHODS: All AAV …
Authors
Pepper RJ; Chanouzas D; Tarzi R; Little MA; Casian A; Walsh M; Pusey CD; Harper L; Salama AD
Journal
Clinical Journal of the American Society of Nephrology, Vol. 8, No. 2, pp. 219–224
Publisher
Wolters Kluwer
Publication Date
2 2013
DOI
10.2215/cjn.03680412
ISSN
1555-9041