Journal article
Tuning Gelation Time and Morphology of Injectable Hydrogels Using Ketone–Hydrazide Cross-Linking
Abstract
Injectable, covalently in situ forming hydrogels based on poly(N-isopropylacrylamide) have been designed on the basis of mixing hydrazide-functionalized nucleophilic precursor polymers with electrophilic precursor polymers functionalized with a combination of ketone (slow reacting) and aldehyde (fast reacting) functional groups. By tuning the ratio of aldehyde:ketone functional groups as well as the total number of ketone groups in the …
Authors
Patenaude M; Campbell S; Kinio D; Hoare T
Journal
Biomacromolecules, Vol. 15, No. 3, pp. 781–790
Publisher
American Chemical Society (ACS)
Publication Date
March 10, 2014
DOI
10.1021/bm401615d
ISSN
1525-7797