Quality of oral anticoagulant control and treatment in Sweden. Duration of Anticoagulation (DURAC) Trial Study Group.

OBJECTIVES: To define laboratory-dependent and clinical factors that negatively influence the precision and safety of oral anticoagulation and to determine whether this creates differences in clinical outcome between the participating hospitals. DESIGN: Laboratory. The clinical chemistry laboratories of participating hospitals performed prothrombin time tests on blinded, standardized plasma samples on six occasions. Clinical. Patients with a …