Integrative Beurteilung der Evidenz im Gesundheitswesen: das GRADE System

Decisions are a double-edged sword: they always and inevitably come with positive and negative consequences. Decisions in healthcare--from a systems level to the individual patient--are not different. This approach acknowledges that for all recommendations and decisions all the important consequences need to be considered. Along these lines, one must evaluate the certainty that estimates of effects and decisions are likely to be correct. Thus, …