Journal article
Alcohol dehydrogenase 3 genotype modification of the associationof alcohol consumption with breast cancer risk
Abstract
Objectives: Because alcohol dehydrogenase 3 (ADH3) is rate-limiting in alcohol oxidation and is polymorphic, we examined ADH3 genotype in relation to alcohol intake and breast cancer risk.Methods: We conducted a case–control study among Caucasian women aged 40–85 with incident, pathologically confirmed breast cancer and controls, frequency-matched on age and county. Queries included alcohol intake in the past 20 years. Genomic DNA was genotyped …
Authors
Freudenheim JL; Ambrosone CB; Moysich KB; Vena JE; Graham S; Marshall JR; Muti P; Laughlin R; Nemoto T; Harty LC
Journal
Cancer Causes & Control, Vol. 10, No. 5, pp. 369–377
Publisher
Springer Nature
Publication Date
August 1999
DOI
10.1023/a:1008950717205
ISSN
0957-5243