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Circulating levels of insulin‐like growth factor‐I...
Journal article

Circulating levels of insulin‐like growth factor‐I and risk of ovarian cancer

Abstract

Insulin-like growth factor (IGF)-I, a mitogenic and anti-apoptotic peptide, has been implicated in the development of several cancers. We hypothesized that high circulating IGF-I concentrations may be associated with an increased risk of ovarian cancer. A case-control study was nested within 3 prospective cohorts in New York (USA), Umeå (Sweden) and Milan (Italy). One hundred thirty-two women with primary invasive epithelial ovarian cancer …

Authors

Lukanova A; Lundin E; Toniolo P; Micheli A; Akhmedkhanov A; Rinaldi S; Muti P; Lenner P; Biessy C; Krogh V

Journal

International Journal of Cancer, Vol. 101, No. 6, pp. 549–554

Publisher

Wiley

Publication Date

October 20, 2002

DOI

10.1002/ijc.10613

ISSN

0020-7136