selected scholarly activity
-
chapters
- Chapter 3 Pluripotent Stem Cell Microenvironment. 33-49. 2017
- Pluripotent Stem Cell Microenvironment. 33-49. 2017
- Chapter 25 Genetic Approaches in Human Embryonic Stem Cells and their Derivatives Prospects for Regenerative Medicine. 311-325. 2013
- Genetic Approaches in Human Embryonic Stem Cells and their Derivatives. 311-325. 2013
- Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine. 311-325. 2012
- Chapter 9 Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine. 179-198. 2011
- Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine. 179-198. 2011
- Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine. 179-198. 2010
- 11 Genetic Approaches in Human Embryonic Stem Cells and Their Derivatives. 190-209. 2008
- Genetic Approaches in Human Embryonic Stem Cells and Their Derivatives. 190-209. 2008
- Part F: Directed Differentiation of Human Embryonic Stem Cells into Myeloid Cells. 299-325. 2007
- CHAPTER 18 Hematopoiesis from Human Embryonic Stem Cells. 238-252. 2007
- Genetic Approaches in Human Embryonic Stem Cells and Their Derivatives. 190-209. 2007
- Hematopoiesis from Human Embryonic Stem Cells. 238-252. 2007
- Hematopoietic Differentiation. 53-83. 2007
- Retroviral Transduction of Hematopoietic Progenitors Derived From Human Embryonic Stem Cells. Methods in molecular biology (Clifton, N.J.). 201-220. 2006
- 38 Characterization of Human Embryonic Stem Cells. 407-411. 2004
- 50 Generation of Precursors and Primitive Human Hematopoietic Cells from Human ESC Lines. 521-528. 2004
- Characterization of Human Embryonic Stem Cells. 407-411. 2004
- Generation of Precursors and Primitive Human Hematopoietic Cells from Human ESC Lines. 521-528. 2004
- Abstracts. Advances in Experimental Medicine and Biology. 157-218. 1995
-
conferences
- Elimination of vaso-occlusive crises after exagamglogene autotemcel in patients with severe Sickle Cell Disease. Oncology Research and Treatment. 99-100. 2023
- Novel approaches to define distinct pathways in cancer stem cells. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2013
- NIPAAm Based Cell Delivery Scaffolds for Posterior Segment Therapeutics. Investigative Ophthalmology and Visual Science. 2013
- Bioprinting a hybrid scaffold containing human placenta derived extracellular matrix. Journal of tissue engineering and regenerative medicine. 376-376. 2012
- Decellularized human placental vascular scaffold provides a platform for tissue and organoid engineering. Journal of tissue engineering and regenerative medicine. 169-170. 2012
- Heat-dried human placental ECM supports human amnion derived adherent cell (AMDAC) growth and induces secretion of growth factors and cytokines. Journal of tissue engineering and regenerative medicine. 170-170. 2012
- Recellularization of decellularized human placental vascular scaffolds for bioengineering. Journal of tissue engineering and regenerative medicine. 294-295. 2012
- ALTERNATIVE SOURCES OF HUMAN HEMATOPOIETIC PROGENITORS BY CELLULAR PROGRAMMING. Experimental Hematology. S1-S1. 2011
- Differential Dependence On Wnt Signaling Allows Chemical Mediated Eradication of Human Acute Leukemia without Affecting Normal Blood Stem Cells. Blood. 1343-1344. 2010
- Function & Immunity of Stem Cell‐Derived Hematopoietic Cells. The FASEB Journal. 2009
- Regulation of epigenetic changes at the TNF alpha locus: Developmental regulation and regulation in SLE. Journal of Immunology. S23-S23. 2006
- Glycogen synthase kinase-3 is an in vivo regulator of human hemopoietic stem cells. Transplantation and Cellular Therapy. 106-106. 2006
- Epigenetic regulation of TNF alpha.. Arthritis and Rheumatism. S480-S480. 2005
- Human embryonic stem cell biology and hematopoietic lineage specification. Experimental Hematology. 39-39. 2005
- Epigenetic regulation of TNF alpha in monocytes/macrophages.. Clinical Immunology. S192-S192. 2005
- 25 Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. American Journal of Obstetrics and Gynecology. S79-S79. 2001
- In vivo tracking of prospectively isolated CD34(+)Lin(-) and CD34(-)Lin(-) subsets reveals functional regulation among cells within the human stem cell compartment.. Blood. 116B-116B. 2001
- Cytokine responsiveness of circulating human embryonic hematopoietic stem cells is unique compared to other stages of human ontogeny.. Blood. 280A-280A. 2000
- Human cord blood Lin-CD45-cells are capable of both hematopoietic and chondrocytic function.. Blood. 281A-281A. 2000
- Human homologs of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells.. Blood. 139B-139B. 2000
- Induction of hematopoietic cell fate from neuronal and muscle cells in the human.. Blood. 277A-277A. 2000
- Isolation of CD34-AC133+LIN- cells from the human stem cell compartment reveals superior retroviral transduction to that of CD34+CD38-LIN-.. Blood. 218A-218A. 2000
- Number of viable CD34+cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation.. Blood. 381A-381A. 2000
- Proteomic analysis of the beta-arrestin signaling complex in chemokine receptor signal transduction.. Blood. 607A-+. 2000
- Quantitative frequency analysis of human stem cells in ex vivo cultures reveals the existence of a pre-SCID repopulating cell (Pre-SRC).. Blood. 124B-124B. 2000
- The human homologs of Sonic hedgehog induces proliferation of primitive human hematopoietic stem cells via regulation of BMP-4.. Blood. 679A-679A. 2000
- The notch ligand Jagged-1 represents a novel growth factor of human hematopoietic stem cells.. Blood. 680A-680A. 2000
- Cell cycle status of human fetal and cord blood cells capable of multilineage repopulation in NOD/SCID mice.. Blood. 654A-654A. 1999
- Characterization of circulating human hematopoietic stem cells during in utero development.. Blood. 36A-36A. 1999
- Isolation of human stem cells capable of multilineage repopulation is not dependent on the level of CXCR4 expression.. Blood. 465A-465A. 1999
- Role of hedgehog proteins in human hematopoietic stem cell development.. Blood. 475A-475A. 1999
- The expression of chemokine receptors on primitive human hematopoietic cells.. Blood. 477A-477A. 1999
- Development of conditions for the ex vivo culture of a novel CD34 negative population of primitive human hematopoietic repopulating cells.. Blood. 703-703. 1997
- Identification of a novel CD34 negative population of primitive human hematopoietic cells capable of repopulating NOS/SCID mice.. Blood. 1134-1134. 1997
- FLT3 ligand downregulates B-lymphopoiesis in NOD/SCID mice engrafted with CD34(++)/38(-) hematopoietic stem cells. Blood. 170-170. 1996
- Phenotypic characterization of a primitive human hematopoietic cell capable of repopulating NOD-SCID mice.. Experimental Hematology. 59-59. 1996
- EXPRESSION OF POLY (ADP-RIBOSE) POLYMERASE (PARP) IN THE DIFFERENTIATION OF MYELOCYTIC-LEUKEMIA CELLS. The FASEB Journal. A124-A124. 1994
-
journal articles
- Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs. Cancer Letters. 599:217108-217108. 2024
- Identification of cells of leukemic stem cell origin with non-canonical regenerative properties. Cell Reports Medicine. 5:101485-101485. 2024
- Targeting cancer cell dormancy. Nature Reviews Cancer. 24:97-104. 2024
- Chemical genomics reveals targetable programs of human cancers rooted in pluripotency. Cell Chemical Biology. 30:780-794.e8. 2023
- Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia. Cell Reports Medicine. 4:101108-101108. 2023
- Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy. Stem cells translational medicine. 12:334-354. 2023
- Evidence-based support for phenotypic drug discovery in acute myeloid leukemia. Drug Discovery Today. 27:103407-103407. 2022
- Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers. Cell Reports. 40:111241-111241. 2022
- Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression. Cells. 11:1915-1915. 2022
- Biting into a union of oncology and metabolism through leukemic stem cells. Cell Metabolism. 34:801-802. 2022
- Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening. Molecules. 27:2434-2434. 2022
- Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics. Cell Chemical Biology. 28:1394-1406.e10. 2021
- Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients. Cell Reports. 34:108845-108845. 2021
- Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions. Cell Reports. 34:108818-108818. 2021
- Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients. Cell Reports Medicine. 2:100202-100202. 2021
- Chemotherapy-Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood. Stem cells translational medicine. 8:1180-1191. 2019
- Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells. Cell. 177:910-924.e22. 2019
- Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence. Cancer Cell. 34:483-498.e5. 2018
- A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia. Blood Advances. 2:1935-1945. 2018
- Author Correction: Direct conversion of human fibroblasts to multilineage blood progenitors. Nature. 560:E32-E32. 2018
- CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure. Stem Cell Reports. 10:1625-1641. 2018
- Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche. Nature Cell Biology. 19:1336-1347. 2017
- Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations. Stem Cells. 35:2095-2102. 2017
- Sam68 Allows Selective Targeting of Human Cancer Stem Cells. Cell Chemical Biology. 24:833-844.e9. 2017
- Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency. Cell Reports. 19:20-35. 2017
- Meet Our Editorial Board Member. Current Stem Cell Research and Therapy. 11:603-603. 2016
- GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia. Cancer Cell. 29:61-74. 2016
- Hypoxia factors suffocate leukemic stem cell initiation. Journal of Experimental Medicine (JEM). 212:2187-2188. 2015
- Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells. Clinical Cancer Research. 21:5324-5337. 2015
- STEM-23PYRVINIUM TARGETS CD133 IN HUMAN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS. Neuro-Oncology. 17:v213.1-v213. 2015
- Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells. Oncotarget. 6:22258-22269. 2015
- Playing musical chairs with bone marrow transplantation to eliminate leukemia stem cells. Molecular and Cellular Oncology. 2:e988480-e988480. 2015
- Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts. Stem Cell Research. 15:221-230. 2015
- Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media. Stem Cell Research. 15:240-242. 2015
- Innate immune response of human pluripotent stem cell-derived airway epithelium. Innate immunity. 21:504-511. 2015
- Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations. Stem Cells. 33:1839-1849. 2015
- Single Transcription Factor Conversion of Human Blood Fate to NPCs with CNS and PNS Developmental Capacity. Cell Reports. 11:1367-1376. 2015
- Reversible Lineage-Specific Priming of Human Embryonic Stem Cells Can Be Exploited to Optimize the Yield of Differentiated Cells. Stem Cells. 33:1142-1152. 2015
- Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states. Nature Communications. 5:5605. 2014
- Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells. Clinical Cancer Research. 20:5372-5378. 2014
- Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human. EMBO Reports. 15:1128-1138. 2014
- Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs. Journal of Experimental Medicine (JEM). 211:1925-1935. 2014
- Activation of Neural Cell Fate Programs Toward Direct Conversion of Adult Human Fibroblasts into Tri-Potent Neural Progenitors Using OCT-4. Stem Cells and Development. 23:1937-1946. 2014
- Molecular Evidence for OCT4-Induced Plasticity in Adult Human Fibroblasts Required for Direct Cell Fate Conversion to Lineage Specific Progenitors. Stem Cells. 32:2178-2187. 2014
- Bone marrow localization and functional properties of human hematopoietic stem cells. Current Opinion in Hematology. 21:249-255. 2014
- Driving human–mouse avatars to understand the HSC niche. Cell Cycle. 13:1511-1512. 2014
- Expansive Generation of Functional Airway Epithelium From Human Embryonic Stem Cells. Stem cells translational medicine. 3:7-17. 2014
- Foundational concepts of cell fate conversion to the hematopoietic lineage. Current Opinion in Genetics and Development. 23:585-590. 2013
- Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors. Experimental Hematology. 41:858-869.e4. 2013
- Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. Blood. 122:1162-1173. 2013
- Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs. Cell Stem Cell. 13:175-189. 2013
- Translating Stem Cells From Laboratory to Clinic. BioPharm International. 26:40-45. 2013
- Gli3-mediated hedgehog inhibition in human pluripotent stem cells initiates and augments developmental programming of adult hematopoiesis. Blood. 121:1543-1552. 2013
- Lengthened G1 Phase Indicates Differentiation Status in Human Embryonic Stem Cells. Stem Cells and Development. 22:279-295. 2013
- Histone Modification Profiling in Normal and Transformed Human Embryonic Stem Cells Using Micro Chromatin Immunoprecipitation, Scalable to Genome-Wide Microarray Analyses. Methods in molecular biology (Clifton, N.J.). 1029:149-161. 2013
- Human Embryonic Stem Cell-Derived Hematopoietic Cells Maintain Core Epigenetic Machinery of the Polycomb Group/Trithorax Group Complexes Distinctly from Functional Adult Hematopoietic Stem Cells. Stem Cells and Development. 22:73-89. 2013
- Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells. Archives of Pharmacal Research. 35:1979-1988. 2012
- Activin A Promotes Hematopoietic Fated Mesoderm Development Through Upregulation of Brachyury in Human Embryonic Stem Cells. Stem Cells and Development. 21:2866-2877. 2012
- Human pluripotency: A difficult state to make smart choices. Cell Cycle. 11:2411-2412. 2012
- Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells. Cell. 149:1284-1297. 2012
- In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation. Stem Cells. 30:392-404. 2012
- Inability of Human Induced Pluripotent Stem Cell-Hematopoietic Derivatives to Downregulate MicroRNAs In Vivo Reveals a Block in Xenograft Hematopoietic Regeneration. Stem Cells. 30:131-139. 2012
- Evidence for the transmission of neoplastic properties from transformed to normal human stem cells. Oncogene. 30:4632-4644. 2011
- Cell Fate Potential of Human Pluripotent Stem Cells Is Encoded by Histone Modifications. Cell Cycle. 9:24-36. 2011
- Identification of T-lymphocytic leukemia–initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. Blood. 117:7112-7120. 2011
- ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis. Journal of Cell Science. 124:1445-1452. 2011
- iPSC Technology: Platform for Drug Discovery. Clinical Pharmacology and Therapeutics. 89:639-641. 2011
- Brief Report: Ectopic Expression of Nup98-HoxA10 Augments Erythroid Differentiation of Human Embryonic Stem Cells. Stem Cells. 29:736-741. 2011
- Clonal interrogation of stem cells. Nature Methods. 8:S36-S40. 2011
- Direct conversion of human fibroblasts to multilineage blood progenitors. Nature. 468:521-526. 2010
- Differential Dependence On Wnt Signaling Allows Chemical Mediated Eradication of Human Acute Leukemia without Affecting Normal Blood Stem Cells. Blood. 116:3278-3278. 2010
- Clonal tracking of hESCs reveals differential contribution to functional assays. Nature Methods. 7:917-922. 2010
- The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood. 116:1433-1442. 2010
- Multiparameter comparisons of embryoid body differentiation toward human stem cell applications. Stem Cell Research. 5:120-130. 2010
- Microenvironment Mimicry. Science. 329:1024-1025. 2010
- Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity . Stem Cells. 28:1379-1389. 2010
- Human ESC colony formation is dependent on interplay between self‐renewing hESCs and unique precursors responsible for niche generation. Cytometry Part B - Clinical Cytometry. 77A:321-327. 2010
- Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men. Stem Cells. 28:419-430. 2010
- Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells. International Journal of Developmental Biology. 54:955-963. 2010
- Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells. PLoS ONE. 4:e8065-e8065. 2009
- Mickie Bhatia: Embryonic stem cells come of age. Journal of Experimental Medicine (JEM). 206:2056-2057. 2009
- Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nature Methods. 6:370-376. 2009
- Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells. Cell Stem Cell. 4:464-464. 2009
- An Enhanced Mass Spectrometry Approach Reveals Human Embryonic Stem Cell Growth Factors in Culture. Molecular & Cellular Proteomics. 8:421-432. 2009
- Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells. Cell Stem Cell. 4:248-262. 2009
- Characterization of human embryonic stem cells with features of neoplastic progression. Nature Biotechnology. 27:91-97. 2009
- OP9 Stroma Augments Survival of Hematopoietic Precursors and Progenitors During Hematopoietic Differentiation from Human Embryonic Stem Cells. Stem Cells. 26:2485-2495. 2008
- Prevention of Amino Acid Conversion in SILAC Experiments with Embryonic Stem Cells. Molecular & Cellular Proteomics. 7:1587-1597. 2008
- The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation. Molecular and Cellular Biology. 28:5312-5327. 2008
- Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency. Journal of Molecular Medicine. 86:875-886. 2008
- Pluripotent human stem cell lines: what we can learn about cancer initiation. Trends in Molecular Medicine. 14:323-332. 2008
- Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects. Current Opinion in Hematology. 15:319-325. 2008
- Targeting LSCs: powering an old tool. Blood. 111:5423-5424. 2008
- Human Embryonic Stem Cells: Lessons from Stem Cell Niches in vivo. Regenerative Medicine. 3:365-376. 2008
- Transplantation of human hematopoietic repopulating cells: mechanisms of regeneration and differentiation using human???mouse xenografts. Current Opinion in Organ Transplantation. 13:44-52. 2008
- A not-so-rough guide to genes and cloning. Nature Cell Biology. 9:1336-1336. 2007
- Formation and Hematopoietic Differentiation of Human Embryoid Bodies by Suspension and Hanging Drop Cultures. Current Protocols in Stem Cell Biology. 3:Unit-1D.2. 2007
- IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature. 448:1015-1021. 2007
- Epigenetic Regulation of Tumor Necrosis Factor Alpha. Molecular and Cellular Biology. 27:5147-5160. 2007
- Early cardiac development: A Wnt beat away. Proceedings of the National Academy of Sciences of the United States of America. 104:9549-9550. 2007
- Hematopoiesis from Human Embryonic Stem Cells. Annals of the New York Academy of Sciences. 1106:219-222. 2007
- Hematopoietic Development from Human Embryonic Stem Cells. Hematology. American Society of Hematology. Education Program. 2007:11-16. 2007
- Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nature Methods. 3:807-815. 2006
- Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells. Nature Medicine. 12:1113-1114. 2006
- Hematopoietic stem cell biology: too much of a Wnt thing. Nature Immunology. 7:1021-1023. 2006
- Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proceedings of the National Academy of Sciences of the United States of America. 103:14134-14139. 2006
- Cellules souches embryonnaires humaines et hématopoïèse. Medecine/sciences. 22:705-707. 2006
- Derivation and Characterization of Hematopoietic Cells From Human Embryonic Stem Cells. Methods in molecular biology (Clifton, N.J.). 331:179-200. 2006
- Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nature Medicine. 12:89-98. 2006
- Retroviral Transduction of Hematopoietic Progenitors Derived From Human Embryonic Stem Cells. Methods in molecular biology (Clifton, N.J.). 331:201-220. 2006
- Intra–bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/β2m−/− mice. Experimental Hematology. 33:1417-1426. 2005
- A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis. Journal of Cell Science. 118:4343-4352. 2005
- Analysis of the Human Fetal Liver Hematopoietic Microenvironment. Stem Cells and Development. 14:493-504. 2005
- Hematopoietic development from human embryonic stem cell lines. Experimental Hematology. 33:987-996. 2005
- Genetic Manipulation of Human Embryonic Stem Cells: A System to Study Early Human Development and Potential Therapeutic Applications. Current Gene Therapy. 5:375-385. 2005
- Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML. Bone Marrow Transplantation. 36:269-270. 2005
- Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood. 105:4598-4603. 2005
- Derivation of the Hematopoietic Stem Cell Compartment from Human Embryonic Stem Cell Lines. Annals of the New York Academy of Sciences. 1044:24-28. 2005
- Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopicHOXB4expression. Journal of Experimental Medicine (JEM). 201:1603-1614. 2005
- Hierarchical and Ontogenic Positions Serve to Define the Molecular Basis of Human Hematopoietic Stem Cell Behavior. Developmental Cell. 8:651-663. 2005
- Hematopoietic capacity of adult human skeletal muscle is negligible. Bone Marrow Transplantation. 35:663-666. 2005
- Challenging the role of Notch in HSC biology. Blood. 105:2248-2248. 2005
- Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Blood. 105:1905-1915. 2005
- Identification of growth factor conditions that reduce ex vivo cord blood progenitor expansion but do not alter human repopulating cell function in vivo.. Hematology Journal. 90:166-172. 2005
- Human Embryonic Stem Cells: Potential Tool for Achieving Immunotolerance?. STEM CELL REVIEWS AND REPORTS. 1:151-158. 2005
- Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45negPFV hemogenic precursors. Molecular Therapy. 10:1109-1120. 2004
- Identification of a novel population of human cord blood cells with hematopoietic and chondrocytic potential. Cell Research. 14:268-282. 2004
- Endothelial and Hematopoietic Cell Fate of Human Embryonic Stem Cells Originates from Primitive Endothelium with Hemangioblastic Properties. Immunity. 21:31-41. 2004
- Human Embryonic Stem Cells Possess Immune‐Privileged Properties. Stem Cells. 22:448-456. 2004
- Differential gene expression of human stem progenitor cells derived from early stages of in utero human hematopoiesis. Blood. 103:2530-2540. 2004
- VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood. 103:2504-2512. 2004
- Coculture and transplant of purified CD34+Lin− and CD34−Lin− cells reveals functional interaction between repopulating hematopoietic stem cells. Leukemia. 17:1613-1625. 2003
- Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood. 102:906-915. 2003
- Bone marrow–derived stem cells initiate pancreatic regeneration. Nature Biotechnology. 21:763-770. 2003
- Differential response of primitive human CD34− and CD34+ hematopoietic cells to the Notch ligand Jagged-1. Leukemia. 17:1366-1374. 2003
- Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cellsinvivo. Proceedings of the National Academy of Sciences of the United States of America. 100:3422-3427. 2003
- The Ultimate Source of Human Hematopoietic Stem Cells: Thinking Outside the Marrow. Cellular Reprogramming. 5:89-97. 2003
- SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors. Hematology Journal. 4:137-145. 2003
- Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34+ absolute counts and subsets. Bone Marrow Transplantation. 30:851-860. 2002
- Emergence of muscle and neural hematopoiesis in humans. Blood. 100:3193-3202. 2002
- Reply to C Delfini et al. Leukemia. 16:2175-2175. 2002
- Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood. 100:869-878. 2002
- Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. Blood. 100:120-127. 2002
- Human embryonic–derived hematopoietic repopulating cells require distinct factors to sustain in vivo repopulating function. Experimental Hematology. 30:598-605. 2002
- Number of viable CD34+ cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation. Bone Marrow Transplantation. 29:967-972. 2002
- Number of viable CD34+ cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation. Bone Marrow Transplantation. 29:967-972. 2002
- Characterization of Retroviral Gene Transfer into Highly Purified Human CD34− Cells with Primitive Hematopoietic Capacity. Molecular Therapy. 5:635-643. 2002
- AC133 expression in human stem cells. Leukemia. 15:1685-1688. 2001
- Circulating hematopoietic stem cells serve as novel targets for in utero gene therapy. The FASEB Journal. 15:1628-1630. 2001
- Circulating hematopoietic stem cells serve as novel targets for in utero gene therapy.. The FASEB Journal. 15:1628-1630. 2001
- Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood. 97:1960-1967. 2001
- Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood. 97:1960-1967. 2001
- Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nature Immunology. 2:172-180. 2001
- The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression. Proceedings of the National Academy of Sciences of the United States of America. 97:14626-14631. 2000
- Cytokine responsiveness of circulating human embryonic hematopoietic stem cells is unique compared to other stages of human ontogeny. Blood. 96. 2000
- G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death. Journal of Biological Chemistry. 275:38213-38220. 2000
- Human cord blood lin-cd45- cells are capable of both hematopoietic and chondrocytic function. Blood. 96. 2000
- Human homologs of delta-1 and delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood. 96. 2000
- Induction of hematopoietic cell fate from neuronal and muscle cells in the human. Blood. 96. 2000
- Isolation of cd34-ac133+lin- cells from the human stem cell compartment reveals superior retroviral transduction to that of cd34+cd38-lin-. Blood. 96. 2000
- Quantitative frequency analysis of human stem cells in ex vivo cultures reveals the existence of a PRE-SCID repopulating cell (PRE-SRC). Blood. 96. 2000
- The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells. Journal of Experimental Medicine (JEM). 192:1365-1372. 2000
- Characterization of Chemokine Receptors Expressed in Primitive Blood Cells During Human Hematopoietic Ontogeny. Stem Cells. 18:374-381. 2000
- Identification of novel circulating human embryonic blood stem cells. Blood. 96:1740-1747. 2000
- Isolation and characterization of human CD34−Lin− and CD34+Lin− hematopoietic stem cells using cell surface markers AC133 and CD7. Blood. 95:2813-2820. 2000
- Preferential Proliferation and Differentiation of Double-Positive Thymocytes into CD8+ Single-Positive Thymocytes in a Novel Cell Culture Medium. Cellular Immunology. 202:41-53. 2000
- Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells. Journal of Experimental Medicine (JEM). 189:1139-1148. 1999
- Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice. Bone Marrow Transplantation. 23:203-209. 1999
- Treatment of Non-Obese Diabetic (NOD)/Severe-Combined Immunodeficient Mice (SCID) With flt3 Ligand and Interleukin-7 Impairs the B-Lineage Commitment of Repopulating Cells After Transplantation of Human Hematopoietic Cells. Blood. 92:2024-2031. 1998
- Treatment of Non-Obese Diabetic (NOD)/Severe-Combined Immunodeficient Mice (SCID) With flt3 Ligand and Interleukin-7 Impairs the B-Lineage Commitment of Repopulating Cells After Transplantation of Human Hematopoietic Cells. Blood. 92:2024-2031. 1998
- A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nature Medicine. 4:1038-1045. 1998
- Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture. Journal of Experimental Medicine (JEM). 186:619-624. 1997
- Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94:5320-5325. 1997
- Assay of human stem cells by repopulation of NOD/SCID mice. Stem Cells. 15:199-207. 1997
- Errata. Nature Medicine. 3:93-93. 1997
- Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy (vol 2, pg 1329, 1996). Nature Medicine. 3:93-93. 1997
- Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy. Nature Medicine. 2:1329-1337. 1996
- 1,25-Dihydroxyvitamin D3 Stimulates Expression and Translocation of Protein Kinase Cα and Cδ via a Nongenomic Mechanism and Rapidly Induces Phosphorylation of a 33-kDa Protein in Acute Promyelocytic NB4 Cells. Journal of Biological Chemistry. 271:16090-16096. 1996
- 1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades. Experimental Cell Research. 222:61-69. 1996
- Overexpression of poly(ADP-ribose) polymerase promotes cell cycle arrest and inhibits neutrophilic differentiation of NB4 acute promyelocytic leukemia cells.. Molecular Cancer Research. 7:91-100. 1996
- Monocytic Differentiation of Acute Promyelocytic Leukemia Cells in Response to 1,25-Dihydroxyvitamin D3 Is Independent of Nuclear Receptor Binding. Journal of Biological Chemistry. 270:15962-15965. 1995
- Modulation of poly(ADP-ribose) polymerase during neutrophilic and monocytic differentiation of promyelocytic (NB4) and myelocytic (HL-60) leukaemia cells. Biochemical Journal. 308:131-137. 1995
- M-CSF and 1,25 dihydroxy vitamin D3 synergize with 12-O-tetradecanoylphorbol-13-acetate to induce macrophage differentiation in acute promyelocytic leukemia NB4 cells.. Leukemia. 8:1744-1749. 1994
- Expansion of Primary Human AML by Aryl Hydrocarbon Receptor Antagonism Minimally Affects Leukemic Transcriptional Profiles but Alters Cellular Metabolism. Journal of Hematology Research. 2:9-16.
- Pluripotent caricatures. Nature Reports Stem Cells. 1-1.