selected scholarly activity
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chapters
- On-Pump and Off-Pump Coronary Revascularization Surgery. 435-448. 2021
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conferences
- PHASE 2 STUDY INTERIM RESULTS OF RBT-1 EFFECT ON POSTOPERATIVE COURSE IN ELECTIVE CABG/VALVE SURGERY. Critical Care Medicine. 2-2. 2023
- Electrocardiographic Changes After Cardiac Surgery and 30-Day Mortality. Circulation. E587-E587. 2022
- Interim Results of a Phase 2 Study With RBT-1 Evaluating Postoperative Course in Patients Undergoing Elective CABG/Valve Surgery on Cardiopulmonary Bypass. Circulation. E587-E588. 2022
- Development and Implementation of an Extracorporeal Membrane Oxygenation (ECMO) Program During the COVID-19 Pandemic: A Single-Center Experience. American Journal of Respiratory and Critical Care Medicine. 2022
- High-sensitivity troponin I predicts major cardiovascular events after noncardiac surgery. European Heart Journal. 1675-1675. 2020
- Perioperative atrial fibrillation and risk of stroke after cardiac surgery: a systematic review and meta-analysis. European Heart Journal. 518-518. 2020
- Vitamin K antagonists versus direct oral anticoagulants after cardiac surgery: a 31-country cohort study. European Heart Journal. 655-655. 2020
- Postoperative atrial fibrillation and long-term risk of stroke and death following cardiac surgery: A systematic review and meta-analysis. BMC Proceedings. O4-O4. 2020
- Method development and validation of tranexamic acid by LC-MS/MS. Clinical Biochemistry. 90-90. 2019
- COST-EFFECTIVENESS OF RIVAROXABAN IN THE TREATMENT OF PATIENTS WITH CHRONIC CAD OR PAD IN THE UK. Value in Health. S550-S550. 2019
- INTERVENTIONAL CARDIOLOGIST POINT OF CARE TREATMENT DECISION VERSUS VIRTUAL HEART TEAM RETROSPECTIVE EVALUATION OF MULTIVESSEL CORONARY ARTERY DISEASE: DIFFERENCES OF OPINION. Journal of the American College of Cardiology. 93-93. 2019
- Benzodiazepine-free cardiac anesthesia for reduction of delirium (B-Free): a two-centre pilot study to determine the feasibility of a multi-centre, randomized, cluster crossover trial. European Heart Journal. 150-150. 2018
- Costs Impact Rivaroxaban Plus Aspirin versus Aspirin in the COMPASS Trial. Circulation. E456-E457. 2017
- Impact of Rivaroxaban Alone or in Combination With Aspirin versus Aspirin in Preventing Graft Occlusion in Patients With CABG Surgery COMPASS CABG. Circulation. 2017
- Marked Global Variability in Cost Effectiveness of Lipid-Lowering and Combination Antihypertensive Therapies in Primary Prevention: Analyses of the HOPE-3 Trial. Circulation. 2017
- Predictors of cognitive decline after cardiac surgery: an evaluation of the CABG off or on pump revascularization study (CORONARY) cohort. European Heart Journal. 445-446. 2017
- Steroids in cardiac surgery (SIRS): infection substudy. European Heart Journal. 1276-1276. 2017
- Surgical ablation of atrial fibrillation evaluation (SAFE): a cost analysis. European Heart Journal. 667-667. 2017
- Surgical ablation of atrial fibrillation ablation in 11 countries: the LAAOS III trial. European Heart Journal. 280-280. 2016
- An evaluation of the incidence and prognosis of post coronary artery bypass grafting myocardial infarction according to different definitions in the CORONARY trial. European Heart Journal. 360-360. 2015
- An event driven myocardial infarction definition using troponins after coronary artery bypass surgery in the coronary trial. European Heart Journal. 997-997. 2015
- A Landmark Analysis of 30-day Mortality after Coronary Artery Bypass Surgery in Patients with Ischemic Heart Failure: Results of the Surgical Treatment for Ischemic Heart Failure (STICH) Trial. Circulation. 2014
- Model-based cost-consequence analysis of postoperative Troponin T screening in patients undergoing noncardiac surgery - case dection. Swiss Medical Weekly. 9S-9S. 2013
- Model-based cost-consequence analysis of postoperative Troponin T screening in patients undergoing noncardiac surgery-1-year. Swiss Medical Weekly. 9S-9S. 2013
- One Year Survival and Predictors of Mortality in Cardiac Surgery Patients With Prolonged Intensive Care Unit Stay. Canadian Journal of Cardiology. S205-S206. 2013
- COST-CONSEQUENCE ANALYSIS OF TROPONIN T SCREENING ON THE DETECTION OF PERIOPERATIVE MYOCARDIAL ISCHEMIA. Anesthesia and Analgesia. 119-119. 2013
- 901 Importance of Risk Stratification to Explain International Variations in Results of the Coronary Trial (Off-Pump Vs. On-Pump Cabg Surgery) — the Canadian Results. Canadian Journal of Cardiology. S416-S417. 2012
- 533 Impact of clopidogrel on patients with ACS undergoing coronary bypass surgery: The practice study. Canadian Journal of Cardiology. S254-S254. 2011
- Randomized Trial of Fondaparinux versus Heparin to Prevent Graft Failure After Coronary Artery Bypass Grafting: The Fonda CABG Pilot Study. Circulation. 2010
- IMPACT OF CLOPIDOGREL ON PATIENTS WITH ACS UNDERGOING CORONARY BYPASS SURGERY: THE PRACTICE STUDY. Canadian Journal of Cardiology. 144D-144D. 2010
- RANDOMIZED TRIAL OF FONDAPARINUX VERSUS HEPARIN TO PREVENT GRAFT FAILURE AFTER CORONARY ARTERY BYPASS GRAFTING: THE FONDA CABG PILOT STUDY. Canadian Journal of Cardiology. 114D-114D. 2010
- Will implementing a syncope assessment algorithm at emergency room reduce hospital admissions and health care costs?. European Heart Journal. 378-378. 2006
- Postoperative risk of mortality after coronary artery bypass graft (CABG) surgery in Canada; The EuroSCORE and the STS algorithms.. American Journal of Epidemiology. S68-S68. 2005
- Cost comparison of four revascularization procedures in patients with multi-vessel coronary artery disease. Journal of the American College of Cardiology. 349A-349A. 2005
- Short-term and long-term outcomes of off-pump and on-pump coronary artery bypass graft surgery: The Canadian off-pump CABG registry. Journal of the American College of Cardiology. 222A-222A. 2005
- One-year cost analysis of off-pump CABG versus on-pump CABG: The Canadian off-pump registry. Circulation. 825-825. 2004
- 1137-77 Long-term cost-effectiveness of clopidogrel in patients having percutaneous coronary intervention early after acute coronary syndrome: Results from PCI-CURE. Journal of the American College of Cardiology. A296-A296. 2004
- Long-term cost effectiveness of platelet inhibition with clopidogrel in patients presenting with acute coronary syndromes: Results from the CURE trial. Circulation. 417-417. 2003
- Long-term cost effectiveness of platelet inhibition with clopidogrel in patients undergoing PCI after presenting with an acute coronary syndrome: Results from PCI-CURE. Circulation. 576-576. 2003
- The Canadian off-pump CABG registry: Interim analysis of early and long-term clinical outcomes. Circulation. 389-390. 2003
- Evaluating the health economic impact of clopidogrel for acute coronary syndromes in five countries, based on the CURE study. Heart. A22-A22. 2003
- Incremental cost-effectiveness of early and long-term clopidogrel in patients undergoing percutaneous coronary infarction in the CURE trial: The PCI-CURE economic analysis. Journal of the American College of Cardiology. 383A-383A. 2003
- The cost-effectiveness of the use of Clopidogrel in acute coronary syndromes based upon the CURE study. Circulation. 758-758. 2002
- Cost analysis of off-pump CABG versus on-pump CABG: Canadian Off-Pump Registry study. Circulation. E106-E106. 2002
- Economic evaluation of the MEDENOX trial: A Canadian perspective.. Blood. 431A-431A. 2001
- Metoprolol prophylaxis against post-operative atrial fibrillation increases length of hospital stay in patients not on pre-operative beta-blockers: The beta-blocker length of stay (BLOS) trial. Circulation. 773-773. 2001
- The extent of ischemic and non-ischemic viable tissue predicts the degree of recovery of LV dysfunction post-revascularization. Journal of the American College of Cardiology. 428A-428A. 2000
- Quality of life in patients with bioprostheses and mechanical prostheses evaluation of cohorts of patients 51-65 years at implantation. Circulation. 2411-2411. 1997
- Gastrointestinal function following esophagectomy for malignancy. American Journal of Surgery. 471-475. 1995
- Giant hydatid lung cysts in the Canadian northwest: Outcome of conservative treatment in three children. Journal of Pediatric Surgery. 1140-1143. 1993
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journal articles
- Secondary Conduits in Coronary Artery Bypass Grafting Surgery.. Annals of Thoracic Surgery. 118:1245-1253. 2024
- A sub-study of the POISE-3 randomized trial examined effects of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury.. Kidney International. S0085-2538(24)00717-8. 2024
- Topical Versus Intravenous Tranexamic Acid in Patients Undergoing Cardiac Surgery: The DEPOSITION Randomized Controlled Trial. Circulation. 150:1315-1323. 2024
- Efficacy and safety of therapeutic alpha-1-microglobulin RMC-035 in reducing kidney injury after cardiac surgery: a multicentre, randomised, double-blind, parallel group, phase 2a trial.. EClinicalMedicine. 76:102830. 2024
- Coronary Artery Bypass Graft Failure in Women. Journal of the American College of Cardiology. 84:182-191. 2024
- Cost effectiveness analysis of a fixed dose combination pill for primary prevention of cardiovascular disease from an individual participant data meta-analysis. EClinicalMedicine. 73:102651-102651. 2024
- RBT-1 reduces blood product utilization in patients undergoing nonemergency coronary artery bypass grafting and/or valve surgery. JTCVS Open. 2024
- Association between overweight and obesity with coronary artery bypass graft failure: an individual patient data analysis of clinical trials. European Journal of Cardio-thoracic Surgery. 65:ezae221. 2024
- The ROMA trial: 7 years of trial activities and the development of the ROMA trial network. European Journal of Cardio-thoracic Surgery. 65:ezae188. 2024
- One-month DAPT with ticagrelor and aspirin for patients undergoing coronary artery bypass grafting: rationale and design of the randomised, multicentre, double-blind, placebo-controlled ODIN trial. EuroIntervention. 20:e322-e328. 2024
- Effects of RBT-1 on preconditioning response biomarkers in patients undergoing coronary artery bypass graft or heart valve surgery: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial. EClinicalMedicine. 68:102364-102364. 2024
- Protein and Exercise to Reverse Frailty in Older Men and Women Undergoing Transcatheter Aortic Valve Replacement: Design of the PERFORM-TAVR Trial. Canadian Journal of Cardiology. 40:267-274. 2024
- One-year Outcomes after Discharge from Noncardiac Surgery and Association between Predischarge Complications and Death after Discharge: Analysis of the VISION Prospective Cohort Study. Anesthesiology. 140:8-24. 2024
- Selecting conduits for coronary artery bypass grafting: caution regarding the right internal mammary artery. Vessel Plus. 8:null-null. 2024
- The Cost-Effectiveness of Rivaroxaban Plus Aspirin Compared with Aspirin Alone in the COMPASS Trial: A US Perspective. American Journal of Cardiovascular Drugs. 24:117-127. 2024
- Cardiac troponin testing in cardiac surgery. Expert Review of Cardiovascular Therapy. 21:729-731. 2023
- Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery. ACP journal club. 176:eL230324. 2023
- Landiolol for the prevention of postoperative atrial fibrillation after cardiac surgery: a systematic review and meta-analysis. Canadian Journal of Anaesthesia. 70:1828-1838. 2023
- Graft Failure After Coronary Artery Bypass Grafting and Its Association With Patient Characteristics and Clinical Events: A Pooled Individual Patient Data Analysis of Clinical Trials With Imaging Follow-Up. Circulation. 148:1305-1315. 2023
- Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium (B-Free): A Protocol for a Multi-centre Randomized Cluster Crossover Trial. CJC OPEN. 5:691-699. 2023
- Perioperative Myocardial Injury/Infarction After Cardiac Surgery. Journal of the American College of Cardiology. 82:1313-1315. 2023
- The cost-effectiveness of rivaroxaban with or without aspirin in the COMPASS trial. European Heart Journal - Quality of Care and Clinical Outcomes. 9:502-510. 2023
- Cost Implications of Left Atrial Appendage Occlusion During Cardiac Surgery: A Cost Analysis of the LAAOS III Trial. Journal of the American Heart Association. 12:e028716. 2023
- Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery. ACP journal club. 176:605-614. 2023
- High-sensitivity Troponin I Predicts Major Cardiovascular Events after Non-Cardiac Surgery: A Vascular Events in Non-Cardiac Surgery Patients Cohort Evaluation (VISION) Substudy. Clinical Chemistry. 69:492-499. 2023
- Five‐Year Hospital Readmission After Coronary Artery Bypass Surgery and the Association With Off‐Pump Surgery and Sex. Journal of the American Heart Association. 12:e028063. 2023
- Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial). BMJ Open. 13:e068363-e068363. 2023
- Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure. British Journal of Anaesthesia. 130:404-411. 2023
- Author Reply to Commentary: Conduit selection in the COMPASS trial: Pointing in the right direction. Journal of Thoracic and Cardiovascular Surgery. 165:1092-1092. 2023
- Conduit selection and early graft failure in coronary artery bypass surgery: A post hoc analysis of the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) coronary artery bypass grafting study. Journal of Thoracic and Cardiovascular Surgery. 165:1080-1089.e1. 2023
- Reply: The right internal mammary artery graft is a mirage. JTCVS Open. 13:199-199. 2023
- Omnia munda mundis (‘to the pure, all things are pure’). European Journal of Cardio-thoracic Surgery. 63:ezad021. 2023
- The impact of statistical properties of incremental monetary net benefit and incremental cost-effectiveness ratio on health economic modeling choices. Expert Review of Pharmacoeconomics and Outcomes Research. 23:69-78. 2023
- Long-Term Treatment with the Combination of Rivaroxaban and Aspirin in Patients with Chronic Coronary or Peripheral Artery Disease: Outcomes During the Open Label Extension of the COMPASS trial. European Heart Journal (EHJ) - Cardiovascular Pharmacotherapy. 8:786-795. 2022
- Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery. Trials. 23:101. 2022
- The cost implications of a polypill for primary prevention in the TIPS-3 trial. European Heart Journal - Quality of Care and Clinical Outcomes. 8:899-908. 2022
- A survey of cardiac surgeons to evaluate the use of sutureless aortic valve replacement in Canada. Journal of Cardiac Surgery. 37:3543-3549. 2022
- Comparison of Investigator-Reported vs Centrally Adjudicated Major Adverse Cardiac Events. JAMA network open. 5:e2243201-e2243201. 2022
- Use of Anticoagulation Therapy in Patients With Perioperative Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Meta-analysis. CJC OPEN. 4:840-847. 2022
- Skeletonized Internal Thoracic Artery—Post Hoc Analysis vs Clinical Practice—Reply. JAMA cardiology. 7:988-988. 2022
- Troponin I after Cardiac Surgery and 30-Day Mortality. New England Journal of Medicine. 386:2342-2343. 2022
- Radial artery versus saphenous vein versus right internal thoracic artery for coronary artery bypass grafting. European Journal of Cardio-thoracic Surgery. 62:ezac345. 2022
- Tranexamic Acid in Patients Undergoing Noncardiac Surgery. New England Journal of Medicine. 386:1986-1997. 2022
- Impact of early quantitative morbidity on 1-year outcomes in coronary artery bypass graft surgery. Interactive Cardiovascular and Thoracic Surgery. 34:523-531. 2022
- High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality. New England Journal of Medicine. 386:827-836. 2022
- Continuous Noninvasive Remote Automated Blood Pressure Monitoring With Novel Wearable Technology: A Preliminary Validation Study. JMIR mHealth and uHealth. 10:e24916-e24916. 2022
- Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial. Canadian Journal of Kidney Health and Disease. 9:205435812110692-205435812110692. 2022
- Short-term and Long-term Risk of Stroke in Patients With Perioperative Atrial Fibrillation After Cardiac Surgery: Systematic Review and Meta-analysis. CJC OPEN. 4:85-96. 2022
- The Cost Implications of Dabigatran in Patients with Myocardial Injury After Non-Cardiac Surgery. American Journal of Cardiovascular Drugs. 22:83-91. 2022
- Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal. 43:18-28. 2021
- Outcomes of sutureless aortic valve replacement versus conventional aortic valve replacement and transcatheter aortic valve replacement, updated systematic review, and meta‐analysis. Journal of Cardiac Surgery. 36:4734-4742. 2021
- Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 144:1133-1144. 2021
- Standardized Assessment of Global activities in the Elderly scale in adult cardiac surgery patients. British Journal of Anaesthesia. 127:539-546. 2021
- Post-discharge after surgery Virtual Care with Remote Automated Monitoring-1 (PVC-RAM-1) technology versus standard care: randomised controlled trial. The BMJ. 374:n2209-n2209. 2021
- Skeletonized vs Pedicled Internal Mammary Artery Graft Harvesting in Coronary Artery Bypass Surgery. JAMA cardiology. 6:1042-1042. 2021
- New‐Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long‐Term Risk of Adverse Events: An Analysis From the CORONARY Trial. Journal of the American Heart Association. 10:e020426. 2021
- Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke. New England Journal of Medicine. 384:2081-2091. 2021
- Commentary: Trials of off- versus on-pump bypass surgery: 105 and counting…. Journal of Thoracic and Cardiovascular Surgery. 161:1283-1284. 2021
- Analysis of serum tranexamic acid in patients undergoing open heart surgery. Clinical Biochemistry. 87:74-78. 2021
- Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study establishing diagnostic criteria and prognostic importance. British Journal of Anaesthesia. 126:163-171. 2021
- Post Discharge after Surgery Virtual Care with Remote Automated Monitoring Technology (PVC-RAM): protocol for a randomized controlled trial. CMAJ open. 9:E142-E148. 2021
- Preoperative prediction of Bleeding Independently associated with Mortality after noncardiac Surgery (BIMS): an international prospective cohort study. British Journal of Anaesthesia. 126:172-180. 2021
- Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes. British Journal of Anaesthesia. 126:56-66. 2021
- Perioperative covert stroke in patients undergoing coronary artery bypass graft surgery. JTCVS Open. 4:1-11. 2020
- Feasibility of studying the association between intraoperative regional cerebral oxygen saturation and postoperative functional decline (ReFUNCTION): a pilot sub-study of NeuroVISION-Cardiac Surgery. Canadian Journal of Anaesthesia. 67:1497-1506. 2020
- Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal of Cardiac Surgery. 35:2754-2758. 2020
- Health economic evaluation of rivaroxaban in the treatment of patients with chronic coronary artery disease or peripheral artery disease. Cardiovascular Research (CVR). 116:1918-1924. 2020
- Comparison of Heart Team vs Interventional Cardiologist Recommendations for the Treatment of Patients With Multivessel Coronary Artery Disease. JAMA network open. 3:e2012749-e2012749. 2020
- Projecting effectiveness after ending a randomized controlled trial: a two-state Markov microsimulation model. International Journal of Technology Assessment in Health Care. 36:317-324. 2020
- Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial. British Journal of Anaesthesia. 125:38-46. 2020
- Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease. Circulation. 141:1841-1854. 2020
- Frailty and Bleeding in Older Adults Undergoing TAVR or SAVR. JACC: Cardiovascular Interventions. 13:1058-1068. 2020
- One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery. Anesthesiology. 132:692-701. 2020
- Randomized Trials in Cardiac Surgery. Journal of the American College of Cardiology. 75:1593-1604. 2020
- Topical Use of Tranexamic Acid in Cardiac Surgery: A Meta-Analysis. Thoracic and Cardiovascular Surgeon. 68:212-218. 2020
- Postoperative Remote Automated Monitoring and Virtual Hospital-to-Home Care System Following Cardiac and Major Vascular Surgery: User Testing Study. Journal of Medical Internet Research. 22:e15548-e15548. 2020
- Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. ACP journal club. 172:96-96. 2020
- Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. The Lancet. 395:698-708. 2020
- Definitions of post-coronary artery bypass grafting myocardial infarction: variations in incidence and prognostic significance. European Journal of Cardio-thoracic Surgery. 57:168-175. 2020
- Hacked by the Russians or fake news. Journal of Thoracic and Cardiovascular Surgery. 158:e46-e47. 2019
- Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators. British Journal of Anaesthesia. 123:228-237. 2019
- The cost implication of primary prevention in the HOPE 3 trial. European Heart Journal - Quality of Care and Clinical Outcomes. 5:266-271. 2019
- Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study. Journal of Cardiac Surgery. 34:305-311. 2019
- Reply. Journal of the American College of Cardiology. 73:2360-2360. 2019
- Habitual Physical Activity in Older Adults Undergoing TAVR. JACC: Cardiovascular Interventions. 12:781-789. 2019
- Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis. British Journal of Anaesthesia. 122:500-508. 2019
- Effect of methylprednisolone on acute kidney injury in patients undergoing cardiac surgery with a cardiopulmonary bypass pump: a randomized controlled trial. CANADIAN MEDICAL ASSOCIATION JOURNAL. 191:E247-E256. 2019
- Sex-Specific Determinants of Outcomes After Transcatheter Aortic Valve Replacement. Circulation. Cardiovascular Quality and Outcomes. 12:e005363. 2019
- Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial. Journal of Thoracic and Cardiovascular Surgery. 157:633-640. 2019
- Examination of psychological risk factors for chronic pain following cardiac surgery: protocol for a prospective observational study. BMJ Open. 9:e022995-e022995. 2019
- Hacked by the Russians. Journal of Thoracic and Cardiovascular Surgery. 157:643-643. 2019
- Steroids in cardiac surgery trial: a substudy of surgical site infections. Canadian Journal of Anaesthesia. 66:182-192. 2019
- Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial. Journal of Thoracic and Cardiovascular Surgery. 157:644-652.e9. 2019
- Rivaroxaban, Aspirin, or Both to Prevent Early Coronary Bypass Graft Occlusion. Journal of the American College of Cardiology. 73:121-130. 2019
- Incidental findings in CT imaging of coronary artery bypass grafts: results from a Canadian multicenter prospective cohort. BMC Research Notes. 11:72. 2018
- Malnutrition and Mortality in Frail and Non-Frail Older Adults Undergoing Aortic Valve Replacement. Circulation. 138:2202-2211. 2018
- Interaction Between Frailty and Access Site in Older Adults Undergoing Transcatheter Aortic Valve Replacement. JACC: Cardiovascular Interventions. 11:2185-2192. 2018
- Postoperative Remote Automated Monitoring: Need for and State of the Science. Canadian Journal of Cardiology. 34:850-862. 2018
- Systematic review and consensus definitions for standardised endpoints in perioperative medicine: postoperative cancer outcomes. British Journal of Anaesthesia. 121:38-44. 2018
- The role of randomized cluster crossover trials for comparative effectiveness testing in anesthesia: design of the Benzodiazepine-Free Cardiac Anesthesia for Reduction in Postoperative Delirium (B-Free) trial. Canadian Journal of Anaesthesia. 65:813-821. 2018
- Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis. Canadian Journal of Surgery. 61:185-194. 2018
- A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia. 120:1066-1079. 2018
- Steroids in cardiac surgery: a systematic review and meta-analysis. British Journal of Anaesthesia. 120:657-667. 2018
- Association of Depression With Mortality in Older Adults Undergoing Transcatheter or Surgical Aortic Valve Replacement. JAMA cardiology. 3:191-191. 2018
- Benzodiazepine administration during adult cardiac surgery: a survey of current practice among Canadian anesthesiologists working in academic centres. Canadian Journal of Anaesthesia. 65:263-271. 2018
- Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery. ACP journal club. 168:237-237. 2018
- Compliance With Guideline-Directed Medical Therapy in Contemporary Coronary Revascularization Trials. Journal of the American College of Cardiology. 71:591-602. 2018
- Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial. The Lancet. 391:205-218. 2018
- Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial. The Lancet. 391:219-229. 2018
- Tranexamic Acid Administration During On-Pump Cardiac Surgery: A Survey of Current Practices Among Canadian Anesthetists Working in Academic Centers. Anesthesia and Analgesia. 125:1863-1870. 2017
- Off-pump Versus On-pump Coronary Artery Bypass Surgery: Graft Patency Assessment With Coronary Computed Tomographic Angiography. Journal of Thoracic Imaging. 32:370-377. 2017
- Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease. New England Journal of Medicine. 377:1319-1330. 2017
- PREDICTORS OF COGNITIVE DECLINE AFTER CARDIAC SURGERY: AN EVALUATION OF THE CABG OFF OR ON PUMP REVASCULARIZATION STUDY (CORONARY) COHORT. Canadian Journal of Cardiology. 33:S36-S36. 2017
- Bleeding impacting mortality after noncardiac surgery: a protocol to establish diagnostic criteria, estimate prognostic importance, and develop and validate a prediction guide in an international prospective cohort study. CMAJ open. 5:E594-E603. 2017
- Frailty in Older Adults Undergoing Aortic Valve Replacement. Journal of the American College of Cardiology. 70:689-700. 2017
- Rationale, Design and Baseline Characteristics of Participants in the C ardiovascular O utco m es for P eople Using A nticoagulation S trategie s (COMPASS) Trial. Canadian Journal of Cardiology. 33:1027-1035. 2017
- Defining clinically important perioperative blood loss and transfusion for the Standardised Endpoints for Perioperative Medicine (StEP) collaborative: a protocol for a scoping review. BMJ Open. 7:e016743-e016743. 2017
- Cost effectiveness of LAA closure in patients with AF and contraindications to warfarin: comment. Europace. 19:euw072-euw072. 2017
- Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. Journal of the American Medical Association (JAMA). 317:1642-1642. 2017
- Simple randomization did not protect against bias in smaller trials. Journal of Clinical Epidemiology. 84:105-113. 2017
- Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Disease. New England Journal of Medicine. 376:1087-1089. 2017
- Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting. New England Journal of Medicine. 376:894-895. 2017
- Conversion after off-pump coronary artery bypass grafting: the CORONARY trial experience. European Journal of Cardio-thoracic Surgery. 51:ezw361-ezw361. 2017
- Coronary Artery Bypass Grafting With and Without Manipulation of the Ascending Aorta. Journal of the American College of Cardiology. 69:924-936. 2017
- The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy. Seminars in Thoracic and Cardiovascular Surgery. 29:35-44. 2017
- Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting. New England Journal of Medicine. 375:2359-2368. 2016
- Long-Term Follow-Up of Outcomes With F-18-Fluorodeoxyglucose Positron Emission Tomography Imaging–Assisted Management of Patients With Severe Left Ventricular Dysfunction Secondary to Coronary Disease. Circulation. Cardiovascular Imaging. 9:e004331. 2016
- Technology-Enabled Remote Monitoring and Self-Management — Vision for Patient Empowerment Following Cardiac and Vascular Surgery: User Testing and Randomized Controlled Trial Protocol. JMIR Research Protocols. 5:e149-e149. 2016
- New Medications for the Treatment of Diabetes. Diabetes Technology and Therapeutics. 18:S112-S129. 2016
- Acute kidney injury after cardiac surgery: Et puis après ?. Journal of Thoracic and Cardiovascular Surgery. 150:1629-1630. 2015
- Methylprednisolone Does Not Reduce Persistent Pain after Cardiac Surgery. Anesthesiology. 123:1404-1410. 2015
- AN EVALUATION OF THE INCIDENCE AND PROGNOSIS OF POST CORONARY ARTERY BYPASS GRAFTING MYOCARDIAL INFARCTION ACCORDING TO DIFFERENT DEFINITIONS IN THE CORONARY TRIAL. Canadian Journal of Cardiology. 31:S161-S161. 2015
- AN EVENT DRIVEN MYOCARDIAL INFARCTION DEFINITION USING TROPONINS AFTER CORONARY ARTERY BYPASS SURGERY IN THE CORONARY TRIAL. Canadian Journal of Cardiology. 31:S161-S162. 2015
- Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial. The Lancet. 386:1243-1253. 2015
- Influence of Baseline Characteristics, Operative Conduct, and Postoperative Course on 30-Day Outcomes of Coronary Artery Bypass Grafting Among Patients With Left Ventricular Dysfunction. Circulation. 132:720-730. 2015
- ISMICS Consensus Conference and Statements of Randomized Controlled Trials of Off-Pump versus Conventional Coronary Artery Bypass Surgery. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 10:219-229. 2015
- Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. New England Journal of Medicine. 372:2387-2397. 2015
- Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. New England Journal of Medicine. 372:1791-1800. 2015
- Cost Implication of an Early Invasive Strategy on Weekdays and Weekends in Patients With Acute Coronary Syndromes. Canadian Journal of Cardiology. 31:314-319. 2015
- Optimising self-management to reduce chronic pain and disability after cardiac surgery. British Journal of Cardiology. 22:38. 2015
- Canadian Institutes of Health Research dissemination grant on high-sensitivity cardiac troponin. Clinical Biochemistry. 47:155-157. 2014
- The Cost Implications of Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery at One Year. Annals of Thoracic Surgery. 98:1620-1625. 2014
- Surviving catastrophic disintegration of a large left atrial myxoma: the importance of multi-disciplinary team. Journal of Surgical Case Reports. 2014:rju093-rju093. 2014
- Cost implications of the use of basal insulin glargine in people with early dysglycemia: The ORIGIN trial. Journal of Diabetes and its Complications. 28:553-558. 2014
- Kidney Function After Off-Pump or On-Pump Coronary Artery Bypass Graft Surgery. Journal of the American Medical Association (JAMA). 311:2191-2191. 2014
- The cost implications of an early versus delayed invasive strategy in acute coronary syndromes: the TIMACS study. Journal of Medical Economics. 17:415-422. 2014
- Effect of Evolocumab or Ezetimibe Added to Moderate- or High-Intensity Statin Therapy on LDL-C Lowering in Patients With Hypercholesterolemia. Journal of the American Medical Association (JAMA). 311:1870-1870. 2014
- Rationale and design of the Steroids in Cardiac Surgery trial. American Heart Journal. 167:660-665. 2014
- Aspirin in Patients Undergoing Noncardiac Surgery. New England Journal of Medicine. 370:1494-1503. 2014
- Clonidine in Patients Undergoing Noncardiac Surgery. New England Journal of Medicine. 370:1504-1513. 2014
- Myocardial Injury after Noncardiac Surgery. Anesthesiology. 120:564-578. 2014
- Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial. BMJ Open. 4:e004842-e004842. 2014
- Left Atrial Appendage Occlusion Study II (LAAOS II). Canadian Journal of Cardiology. 29:1443-1447. 2013
- Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus. New England Journal of Medicine. 369:1317-1326. 2013
- Off-Pump or On-Pump Coronary-Artery Bypass Grafting. New England Journal of Medicine. 369:194-197. 2013
- Clinical outcomes and cost implications of routine early PCI after fibrinolysis: One-year follow-up of the Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI) study. American Heart Journal. 165:630-637.e2. 2013
- Effects of Off-Pump and On-Pump Coronary-Artery Bypass Grafting at 1 Year. New England Journal of Medicine. 368:1179-1188. 2013
- Off-Pump or On-Pump Coronary-Artery Bypass Grafting. New England Journal of Medicine. 367:577-578. 2012
- Off-Pump or On-Pump Coronary-Artery Bypass Grafting REPLY. New England Journal of Medicine. 367:578-578. 2012
- Error in Viewpoint in: Statin Therapy for Healthy Men Identified as ‘Increased Risk,’. Journal of the American Medical Association (JAMA). 307:2590-2590. 2012
- Influence of Mitral Regurgitation Repair on Survival in the Surgical Treatment for Ischemic Heart Failure Trial. Circulation. 125:2639-2648. 2012
- Off-Pump or On-Pump Coronary-Artery Bypass Grafting at 30 Days. New England Journal of Medicine. 366:1489-1497. 2012
- Vorapaxar in the Secondary Prevention of Atherothrombotic Events. New England Journal of Medicine. 366:1404-1413. 2012
- Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood. 119:2172-2174. 2012
- Coronary Artery Bypass Grafting Surgery Off- or On-pump Revascularisation Study (CORONARY): kidney substudy analytic protocol of an international randomised controlled trial. BMJ Open. 2:e001080-e001080. 2012
- Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery. American Heart Journal. 163:1-6. 2012
- The Cost of Clopidogrel Use in Atrial Fibrillation in the ACTIVE-A Trial. Canadian Journal of Cardiology. 28:95-101. 2012
- Randomized trial of fondaparinux versus heparin to prevent graft failure after coronary artery bypass grafting: the Fonda CABG study. Journal of Thrombosis and Thrombolysis. 32:378-385. 2011
- Medical treatment, PCI, or CABG for coronary artery disease?. The BMJ. 342:d966-d966. 2011
- Epicardial fat thickness and coronary artery disease correlate independently of obesity. International Journal of Cardiology. 146:452-454. 2011
- The cost implications of the use of telmisartan or ramipril in patients at high risk for vascular events: the ONTARGET study. Journal of Medical Economics. 14:792-797. 2011
- Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study. American Heart Journal. 160:1178-1184. 2010
- Canadian Registry of ICD Implant Testing Procedures (CREDIT): Current Practice, Risks, and Costs of Intraoperative Defibrillation Testing. Journal of Cardiovascular Electrophysiology. 21:177-182. 2010
- Antithrombotic management of patients with prosthetic heart valves: current evidence and future trends. The Lancet. 374:565-576. 2009
- Para-aortic arch abscess secondary to Staphylococcus aureus pneumonia. Canadian Journal of Cardiology. 25:233-236. 2009
- Acute Kidney Injury After Cardiac Surgery. Circulation. 119:495-502. 2009
- Cardiac surgery in patients with haemophilia B: a case report and review of the literature. Haemophilia. 15:108-113. 2009
- Fluoroscopy of Acutely Thrombosed Aortic Valve. Circulation. 118:e705. 2008
- Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. The Lancet. 372:1174-1183. 2008
- Cost comparison of four revascularisation procedures for the treatment of multivessel coronary artery disease. Journal of Medical Economics. 11:119-134. 2008
- Cost comparison of four revascularisation procedures for the treatment of multivessel coronary artery disease: a commentary. Journal of Medical Economics. 11:1-2. 2008
- Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation. Journal of Thoracic and Cardiovascular Surgery. 135:131-138. 2008
- F-18-Fluorodeoxyglucose Positron Emission Tomography Imaging-Assisted Management of Patients With Severe Left Ventricular Dysfunction and Suspected Coronary Disease. Journal of the American College of Cardiology. 50:2002-2012. 2007
- Early mortality from off-pump and on-pump coronary bypass surgery in Canada: A comparison of the STS and the EuroSCORE risk prediction algorithms. Canadian Journal of Cardiology. 23:879-883. 2007
- A cost comparison of off-pump CABG versus on-pump CABG at one-year: The Canadian Off-Pump CABG Registry. Canadian Journal of Cardiology. 22:699-704. 2006
- Long-term cost-effectiveness of early and sustained clopidogrel therapy for up to 1 year in patients undergoing percutaneous coronary intervention after presenting with acute coronary syndromes without ST-segment elevation. American Heart Journal. 151:219-227. 2006
- Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: The Heart Outcomes Prevention Evaluation (HOPE)-2 trial. Canadian Journal of Cardiology. 22:47-53. 2006
- Nitric oxide-related products and myeloperoxidase in bronchoalveolar lavage fluids from patients with ALI activate NF-kappa B in alveolar cells and monocytes. Vascular Pharmacology. 43:425-433. 2005
- The Canadian off-pump coronary artery bypass graft registry: a one-year prospective comparison with on-pump coronary artery bypass grafting.. Canadian Journal of Cardiology. 21:1175-1181. 2005
- Perivascular adipose tissue modulates vascular function in the human internal thoracic artery. Journal of Thoracic and Cardiovascular Surgery. 130:1130-1136. 2005
- Should Aspirin Be Discontinued Before Coronary Artery Bypass Surgery?. Circulation. 112:e85-e90. 2005
- Left Atrial Appendage Occlusion Study (LAAOS): Results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke. American Heart Journal. 150:288-293. 2005
- Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevation. Journal of the American College of Cardiology. 45:838-845. 2005
- Is Positron Emission Tomography for the Management of Potentially Operable Non‐Small Cell Lung Cancer an Efficient Use of Quebec Health Care Resources?. Canadian Respiratory Journal. 12:11-12. 2005
- The cost-effectiveness of the use of clopidogrel in acute coronary syndromes in five countries based upon the CURE study.. European Journal of Preventive Cardiology (EJPC). 11:460-465. 2004
- Metoprolol prophylaxis against postoperative atrial fibrillation increases length of hospital stay in patients not on pre-operative blockers: the blocker length of stay (BLOS) trial. Heart. 90:941-942. 2004
- Adherence to guidelines for lipid-lowering therapy after coronary artery bypass grafting (CABG): Canadian off-pump CABG registry. Annals of Epidemiology. 13:574-574. 2003
- The effect of oxygenator membranes on blood: a comparison of two oxygenators in open-heart surgery. Perfusion. 18:313-320. 2003
- Cost Implications of the Use of Ramipril in High-Risk Patients Based on the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation. 107:960-965. 2003
- Double-blind, placebo-controlled, randomized trial of prophylactic metoprolol for reduction of hospital length of stay after heart surgery: The β-Blocker Length Of Stay (BLOS) study. American Heart Journal. 145:226-232. 2003
- Left Atrial Appendage Occlusion Study (LAAOS): A randomized clinical trial of left atrial appendage occlusion during routine coronary artery bypass graft surgery for long-term stroke prevention. American Heart Journal. 145:174-178. 2003
- Outcome of major cardiac injuries at a Canadian trauma center. BMC Surgery. 2:4. 2002
- Positron emission tomography and recovery following revascularization (PARR-1): the importance of scar and the development of a prediction rule for the degree of recovery of left ventricular function. Journal of the American College of Cardiology. 40:1735-1743. 2002
- Coronary artery bypass grafting in octogenarians - The authors respond. CANADIAN MEDICAL ASSOCIATION JOURNAL. 166:1395-1396. 2002
- Coronary artery bypass grafting in octogenarians.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 166:1395. 2002
- Economic Evaluation of the MEDENOX Trial: A Canadian Perspective. Canadian Respiratory Journal. 9:169-177. 2002
- Outcomes and costs of coronary artery bypass grafting: comparison between octogenarians and septuagenarians at a tertiary care centre.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 165:759-764. 2001
- Effects of long-term, moderate-intensity oral anticoagulation in addition to aspirin in unstable angina. Journal of the American College of Cardiology. 37:475-484. 2001
- Quality of life in patients with bioprostheses and mechanical prostheses. Evaluation of cohorts of patients aged 51 to 65 years at implantation.. Circulation. 98:II81-II86. 1998
- Transmyocardial laser revascularization may relieve angina and improve myocardial perfusion among patients with angina refractory to medical treatment. Evidence-based Cardiovascular Medicine. 1:77-77. 1997
- PTCA had little cost advantage over CABG in patients with multi-vessel disease. Evidence-based Cardiovascular Medicine. 1:54-54. 1997
- Anterior and middle mediastinum paraganglioma: Complete resection is the treatment of choice. Annals of Thoracic Surgery. 57:249-252. 1994
- Proposed method for analyzing carotid endarterectomy results.. Stroke. 19:1180-1181. 1988
- Intimal hyperplasia and thrombosis of the visceral arteries in a young woman: possible relation with oral contraceptives and smoking.. Surgery. 103:706-710. 1988
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preprints
- Continuous Noninvasive Remote Automated Blood Pressure Monitoring With Novel Wearable Technology: A Preliminary Validation Study (Preprint) 2020
- Postoperative Remote Automated Monitoring and Virtual Hospital-to-Home Care System Following Cardiac and Major Vascular Surgery: User Testing Study (Preprint) 2019