SOMATIC GENE THERAPY FOR CYSTIC FIBROSIS Grant

date/time interval

• September 30, 1993 - August 31, 1998

awarded by

• National Heart Lung and Blood Institute 

total award amount

• USD 5164140

sponsor award ID

• P01HL051754

contributor

• Graham, Frank Lawson   Funded by

supported publications or other works

• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons  Journal Articles
• Gene targeting in mouse embryonic stem cells with an adenoviral vector  Journal Articles
• Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity  Journal Articles
• High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα₁-Antitrypsin with Negligible Toxicity  Journal Articles
• Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.  Journal Articles
• Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector  Journal Articles