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Identification of Multiple Genetic Susceptibility...
Journal article

Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

Abstract

Takayasu arteritis is a rare inflammatory disease of large arteries. The etiology of Takayasu arteritis remains poorly understood, but genetic contribution to the disease pathogenesis is supported by the genetic association with HLA-B*52. We genotyped ~200,000 genetic variants in two ethnically divergent Takayasu arteritis cohorts from Turkey and North America by using a custom-designed genotyping platform (Immunochip). Additional genetic …

Authors

Saruhan-Direskeneli G; Hughes T; Aksu K; Keser G; Coit P; Aydin SZ; Alibaz-Oner F; Kamalı S; Inanc M; Carette S

Journal

American Journal of Human Genetics, Vol. 93, No. 2, pp. 298–305

Publisher

Elsevier

Publication Date

8 2013

DOI

10.1016/j.ajhg.2013.05.026

ISSN

0002-9297