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Reduced Aggressiveness and Low Testosterone Levels...
Journal article

Reduced Aggressiveness and Low Testosterone Levels in Autoimmune MRL-lpr Males

Abstract

Autoimmune, lupus-prone MRL-lpr mice float excessively in the forced swim test, explore novel objects and places less, and show blunted responsiveness to palatable stimuli, which is consistent with the hypothesis that the development of chronic autoimmune disease alters emotional reactivity and/or motivation. The present study measures isolation-induced fighting, a model of "affective" aggression, in lupus-prone MRL-lpr and control MRL +/+ …

Authors

Šakić B; Gurunlian L; Denburg SD

Journal

Physiology & Behavior, Vol. 63, No. 2, pp. 305–309

Publisher

Elsevier

Publication Date

1 1998

DOI

10.1016/s0031-9384(97)00422-8

ISSN

0031-9384