A critical review of brand and generic alendronate for the treatment of osteoporosis

ObjectiveCompare in vitro and in vivo characteristics and clinical outcomes of brand and generic alendronate.Research design and methods: Relevant search terms were input into Medline ("alendronate" AND "generic" up to August 5, 2013) and any abstracts deemed possibly relevant selected for full paper review and abstraction.ResultsMulticentre, randomized, placebo-controlled Phase III clinical trials of substantial size and duration have …