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Genetic Differential Susceptibility to...
Journal article

Genetic Differential Susceptibility to Socioeconomic Status and Childhood Obesogenic Behavior: Why Targeted Prevention May Be the Best Societal Investment

Abstract

IMPORTANCE: Genes may work by modulating the way individuals respond to environmental variation, and these discrete and differential genes vs environmental interactions may not be readily captured in simple association studies. OBJECTIVE: To determine whether children carrying the 7-repeat allele of the DRD4 gene living under adverse economic conditions have worse-than-average fat intake compared with those living in a healthy environment.

Authors

Silveira PP; Gaudreau H; Atkinson L; Fleming AS; Sokolowski MB; Steiner M; Kennedy JL; Meaney MJ; Levitan RD; Dubé L

Journal

JAMA Pediatrics, Vol. 170, No. 4,

Publisher

American Medical Association (AMA)

Publication Date

April 1, 2016

DOI

10.1001/jamapediatrics.2015.4253

ISSN

2168-6203