Journal article
Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle.
Abstract
Cardiac muscle expresses sarcoplasmic/endoplasmic-reticulum Ca2+ pump isoform SERCA2a; stomach smooth muscle expresses SERCA2b. In 2-day-old rabbits, cardiac muscle contained levels of SERCA2 protein that were 100-200-fold those in the stomach smooth muscle. In nuclear run-on assays, the rate of SERCA2 gene transcription in heart nuclei was not significantly higher than in the stomach smooth-muscle nuclei. However, the SERCA2 mRNA levels …
Authors
Misquitta CM; Sing A; Grover AK
Journal
Biochemical Journal, Vol. 338 ( Pt 1), No. 1, pp. 167–173
Publisher
Portland Press
Publication Date
February 15, 1999
DOI
10.1042/0264-6021:3380167
ISSN
0264-6021