Journal article
Proximity of Na+–Ca2+-exchanger and sarco/endoplasmic reticulum Ca2+ pump in pig coronary artery smooth muscle: fluorescence microscopy
Abstract
Pig coronary artery smooth muscle expresses the Na+–Ca2+-exchanger NCX1 and the sarco/endoplasmic reticulum (SER) Ca2+ pump SERCA2. NCX has been proposed to play a role in refilling the SER Ca2+ pool. Caveolae may also direct Ca2+ traffic during cell signaling. Here, we use immunofluorescence microscopy to determine if there is proximity between NCX1, SERCA2, and the caveolar protein caveolin-1. Stacks of images of cell surface domains were …
Authors
Kuszczak I; Kuner R; Samson SE; Grover AK
Journal
Molecular and Cellular Biochemistry, Vol. 339, No. 1-2, pp. 293–300
Publisher
Springer Nature
Publication Date
6 2010
DOI
10.1007/s11010-010-0392-y
ISSN
0300-8177