Journal article
Persistence of Circadian Rhythms of Melatonin and N-Acetylserotonin in the Serum of Rats after Pinealectomy
Abstract
To study the effect of pinealectomy (Px) on the rhythms of serum indoles, male rats were adapted to 12L:12D for 2 weeks after which half of them were Px. The animals were decapitated at 4-hour intervals 1 week after operation. Melatonin (Mel) and N-acetylserotonin (NAS) were extracted and quantified by RIA. The concentrations of serum Mel and NAS were significantly reduced after Px, suggesting that the pineal contributes a significant amount of …
Authors
Yu HS; Pang SF; Tang PL; Brown GM
Journal
Neuroendocrinology, Vol. 32, No. 5, pp. 262–265
Publisher
Karger Publishers
Publication Date
1981
DOI
10.1159/000123170
ISSN
0028-3835