Journal article
Age-associated changes and sex differences in urinary 6-sulphatoxymelatonin circadian rhythm in the rat
Abstract
The circadian rhythm of 6-sulphatoxymelatonin (aMT6s) excretion has been determined in male and female rats at 3 weeks and at 2, 8, 14 and 20 months of age. All animals have a pronounced circadian pattern of aMT6s excretion under a 12 hour dark: 12 hour light cycle. A significant increase in aMT6s excretion is observed from 3 weeks to 14 months followed by a decrease at 20 months. There is a highly significant correlation between aMT6s …
Authors
Yie S-M; Liu G-Y; Johansson E; Brown C; Brown GM
Journal
Life Sciences, Vol. 50, No. 17, pp. 1235–1242
Publisher
Elsevier
Publication Date
January 1992
DOI
10.1016/0024-3205(92)90323-h
ISSN
0024-3205