Journal article
Melatonin in Mitochondrial Dysfunction and Related Disorders
Abstract
Mitochondrial dysfunction is considered one of the major causative factors in the aging process, ischemia/reperfusion (I/R), septic shock, and neurodegenerative disorders like Parkinson's disease (PD), Alzheimer's disease (AD), and Huntington's disease (HD). Increased free radical generation, enhanced mitochondrial inducible nitric oxide (NO) synthase activity, enhanced NO production, decreased respiratory complex activity, impaired electron …
Authors
Srinivasan V; Spence DW; Pandi-Perumal SR; Brown GM; Cardinali DP
Journal
International Journal of Alzheimer's Disease, Vol. 2011, No. 1,
Publisher
Wiley
Publication Date
January 2011
DOI
10.4061/2011/326320
ISSN
2090-8024