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Melatonin and brain inflammaging
Journal article

Melatonin and brain inflammaging

Abstract

Melatonin is known to possess several properties of value for healthy aging, as a direct and indirect antioxidant, protectant and modulator of mitochondrial function, antiexcitotoxic agent, enhancer of circadian amplitudes, immune modulator and neuroprotectant. It is levels tend to decrease in the course of senescence and are more strongly reduced in several neurodegenerative disorders, especially Alzheimer's disease, and in diseases related to …

Authors

Hardeland R; Cardinali DP; Brown GM; Pandi-Perumal SR

Journal

Progress in Neurobiology, Vol. 127, , pp. 46–63

Publisher

Elsevier

Publication Date

4 2015

DOI

10.1016/j.pneurobio.2015.02.001

ISSN

0301-0082