Journal article
Opposite Effects of Arterial Vasodilators on Cardiac vs. Arterial Hypertrophy and Sympathetic Activity in Spontaneously Hypertensive Rats
Abstract
To investigate whether cardiac and arterial structure and sympathetic activity changes in a similar fashion during chronic arterial vasodilation, we evaluated the morphology and sympathetic activity of the mesenteric arterial bed and the left (LV) and right (RV) ventricles of 16-week-old Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHRs) after 35 and 70 days of treatment with the arterial vasodilator minoxidil. The minoxidil-induced …
Authors
Tsoporis J; Fields N; Lee RMKW; Leenen FHH
Journal
Journal of Cardiovascular Pharmacology, Vol. 17, No. Supplement 2, pp. s169–s171
Publisher
Wolters Kluwer
Publication Date
1991
DOI
10.1097/00005344-199117002-00043
ISSN
0160-2446