Journal article
Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets
Abstract
Patients with acute myocardial infarction who undergo thrombolytic therapy may shortly thereafter present evidence for increased platelet activation and thrombin activity, and recurrent thrombosis. This study investigated whether plasmin activates platelets and prothrombin in recalcified platelet-rich plasma (RPRP) to cause (at least in part) these side-effects of thrombolytic therapy. Plasmin (0.1 and 1.0 CU/ml) addition to RPRP with microM …
Authors
Liu L; Freedman J; Hornstein A; Dewar L; Blajchman M; Ofosu F
Journal
British Journal of Haematology, Vol. 92, No. 2, pp. 458–465
Publisher
Wiley
Publication Date
January 1996
DOI
10.1046/j.1365-2141.1996.d01-1467.x
ISSN
0007-1048