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New oral anticoagulants in atrial fibrillation
Journal article

New oral anticoagulants in atrial fibrillation

Abstract

Atrial fibrillation (AF) is a major risk factor for stroke. Currently, acetylsalicylic acid (a platelet inhibitor) and vitamin K antagonists (VKAs; oral anticoagulants), including warfarin, are the only approved antithrombotic therapies for stroke prevention in patients with AF. Although effective, VKAs have unpredictable pharmacological effects, requiring regular coagulation monitoring and dose adjustment to maintain effects within the …

Authors

Turpie AGG

Journal

European Heart Journal, Vol. 29, No. 2, pp. 155–165

Publisher

Oxford University Press (OUP)

Publication Date

January 2008

DOI

10.1093/eurheartj/ehm575

ISSN

0195-668X