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Genomic Instability in Regions Adjacent to a...
Journal article

Genomic Instability in Regions Adjacent to a Highly Conserved pch Prophage in Escherichia coli O157:H7 Generates Diversity in Expression Patterns of the LEE Pathogenicity Island

Abstract

The LEE pathogenicity island has been acquired on multiple occasions within the different lineages of enteropathogenic and enterohemorrhagic Escherichia coli. In each lineage, LEE expression is regulated by complex networks of pathways, including core pathways shared by all lineages and lineage-specific pathways. Within the O157:H7 lineage of enterohemorrhagic E. coli, strain-to-strain variation in LEE expression has been observed, implying …

Authors

Yang Z; Kim J; Zhang C; Zhang M; Nietfeldt J; Southward CM; Surette MG; Kachman SD; Benson AK

Journal

Journal of Bacteriology, Vol. 191, No. 11, pp. 3553–3568

Publisher

American Society for Microbiology

Publication Date

6 2009

DOI

10.1128/jb.01738-08

ISSN

0021-9193