Journal article
Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress
Abstract
BackgroundStress-related disorders involve systemic alterations, including disruption of the intestinal microbial community. Given the putative connections between the microbiota, immunity, neural function, and behaviour, we investigated the potential for microbe-induced gut-to-brain signalling to modulate the impact of stress on host behaviour and immunoregulation.MethodsMale C57BL/6 mice treated orally over 28 days with either Lactobacillus …
Authors
Bharwani A; Mian MF; Surette MG; Bienenstock J; Forsythe P
Journal
BMC Medicine, Vol. 15, No. 1,
Publisher
Springer Nature
Publication Date
12 2017
DOI
10.1186/s12916-016-0771-7
ISSN
1741-7015