Immunometabolism: the interface of immune and metabolic responses in disease

Metabolism and pathogen defense are essential requirements for survival. Mounting an immune response requires major changes to metabolic processes, and immune mediators (such as cytokines) also dictate changes in metabolism, including endocrine regulation of substrate utilization. The April 2014 issue contains a Special Feature on Immunometabolism: The interface of immune and metabolic responses in disease. Further background information on this important topic is available through the accompanying web focus which links to related articles from across Nature Publishing Group.